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      V. Amygdalina: Folk Medicine, Analysis, and Potential Application for Cancer Treatment.

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          Abstract

          Folk medicine (FM) is practiced by people without access to conventional medical services; it usually involves the use of natural remedies such as herbs or vegetable substances. Before the use of pharmaceutical drugs, and surgical procedures, these healing methods were used, and are still in use today. It is estimated that twenty five percent of all therapeutic drugs trace their origins to plants, and almost two-thirds of the people of the world rely on their healing powers. One hundred years ago, health care in the U.S. was provided by a highly competitive medical sect, and quite infrequently, folk medicine practitioners were patronized. However, FM usage in the U.S. has increased drastically during the past decade. National surveys of adults (18 years of age or older) show that one in three adults use unconventional therapies or Complementary and Alternative Medicine (CAM) in the U.S. The rate of CAM usage is more than eighty percent among cancer patients. Vernonia amygdalina (VA) is well known for its medicinal importance. Fractionation of the VA extracts with solvents of varying polarities, by silica gels analyses, UV Spectrophotometer, HPLC, TLC and NMR techniques have yielded some biologically-active fractions.

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          Author and article information

          Journal
          Curr Pharm Anal
          Current pharmaceutical analysis
          Bentham Science Publishers Ltd.
          1573-4129
          1573-4129
          January 1 2008
          : 4
          : 1
          Affiliations
          [1 ] The Laboratory of Cellular Signaling, Phytoceuticals, Cancer Prevention and Therapies, Jackson State University, Jackson, MS 39217, USA; NIH-Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, MS 39217, USA; Department of Biology, Jackson State University, Jackson, MS 39217, USA.
          [2 ] NIH-Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, MS 39217, USA; Department of Biology, Jackson State University, Jackson, MS 39217, USA.
          [3 ] NIH-Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, MS 39217, USA; Department of Chemistry, Jackson State University, Jackson, MS 39217, USA.
          Article
          NIHMS756593
          10.2174/157341208783497579
          4850832
          27134615
          a63fcc60-0ed3-41e8-9cfe-6515a1d0bd37
          History

          Anti-cancer activity,Apoptosis,Sesquiterpene lactones,Vernonia amygdalina extracts

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