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      Functional neuroarchitecture of the retina: hypothesis on the dysfunction of retinal dopaminergic circuitry in Parkinson's disease Translated title: Neuroarchitecture fonctionnelle de la rétine: hypothèse sur le dysfonctionnement des circuits dopaminergiques rétiniens dans la maladie de Parkinson

      Surgical and Radiologic Anatomy
      Springer Science and Business Media LLC

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          Low-contrast letter charts in early diabetic retinopathy, ocular hypertension, glaucoma, and Parkinson's disease.

          Diabetes can cause visual loss that is not detected by standard reading tests such as the Snellen test but can be detected by low-contrast letter charts. This visual loss is quite different from loss caused by refractive error. These low-contrast charts are diagnostically at least as sensitive as the sinewave grating contrast sensitivity test. They are inexpensive, and the test is brief and simple. Preliminary evidence is that patients with diabetes who have abnormal low-contrast chart results give abnormal intravenous fluorescein (IVF) test results, even though visual acuity is normal. Low-contrast charts also detect visual loss in patients with ocular hypertension, glaucoma, and Parkinson's disease, including patients with normal visual acuity.
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            Effects of Aging on Visual Evoked Responses

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              Visual and auditory evoked responses in patients with Parkinson's disease.

              Visual evoked responses were obtained in 47 Parkinsonian patients and 26 age-matched controls. The stimulation to binocular and uniocular latency of the major positive peak was longer in the Parkinsonian patients and its amplitude was smaller than in the control subjects. There was a large interocular difference suggesting that at least part of the delay occurs at prechiasmatic level. The latency and amplitude varied markedly following ingestion of levodopa as Sinemet. Auditory evoked potentials were obtained in 16 Parkinsonian patients and 11 age-matched controls. The latency of the NV wave was prolonged in the former although the amplitude was the same, suggesting that the abnormality may be a widespread one.
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                Author and article information

                Journal
                Surgical and Radiologic Anatomy
                Surg Radiol Anat
                Springer Science and Business Media LLC
                0930-312X
                1279-8517
                June 1988
                June 1988
                : 10
                : 2
                : 137-144
                Article
                10.1007/BF02307822
                a64c367a-ec9e-4d08-ae2d-086842a6f818
                © 1988

                http://www.springer.com/tdm

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