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      Novel type of staphylococcal cassette chromosome mec identified in community-acquired methicillin-resistant Staphylococcus aureus strains.

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          Abstract

          We identified a new type of staphylococcal cassette chromosome mec (SCCmec) from two community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains. The novel element, designated type IV SCCmec, had a unique combination of the class B mec gene complex and the type 2 ccr gene complex and was much smaller in size (21 to 24 kb) than previously identified SCCmec elements of hospital-acquired MRSA. Consistent with the strains' susceptibilities to various non-beta-lactam antibiotics, the type IV SCCmec was devoid of any antibiotic resistance genes other than the mecA gene.

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          Author and article information

          Journal
          Antimicrob Agents Chemother
          Antimicrobial agents and chemotherapy
          American Society for Microbiology
          0066-4804
          0066-4804
          Apr 2002
          : 46
          : 4
          Affiliations
          [1 ] Department of Bacteriology, Juntendo University, Tokyo, Japan.
          Article
          10.1128/AAC.46.4.1147-1152.2002
          127097
          11897611
          a6504efe-63b9-4171-a575-afcb000a0c08
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