For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
3
views
48
references
 Top references
cited by
7
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      896
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Effects of Ashwagandha ( Withania somnifera) on VO 2max: A Systematic Review and Meta-Analysis

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The purpose of this study was to systematically review the scientific literature about the effects of supplementation with Ashwagandha ( Withania somnifera) on maximum oxygen consumption (VO 2max), as well as to provide directions for clinical practice. A systematic search was conducted in three electronic databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA). The inclusion criteria were: (a) VO 2max data, with means ± standard deviation before and after the supplement intervention, (b) the study was randomized controlled trial (RCT), (c) the article was written in English. The quality of evidence was evaluated according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. A meta-analysis was performed to determine effect sizes. Five studies were selected in the systematic review (162 participants) and four were included in the meta-analysis (142 participants). Results showed a significant enhancement in VO 2max in healthy adults and athletes ( p = 0.04). The mean difference was 3.00 (95% CI from 0.18 to 5.82) with high heterogeneity. In conclusion, Ashwagandha supplementation might improve the VO 2max in athlete and non-athlete people. However, further research is need to confirm this hypothesis since the number of studies is limited and the heterogeneity was high.

          Related collections

          Most cited references48

          • Record: found
          • Abstract: found
          • Article: not found

          Influences of cardiorespiratory fitness and other precursors on cardiovascular disease and all-cause mortality in men and women.

          S N Blair, J Kampert, H W Kohl … (1996)
          To quantify the relation of cardiorespiratory fitness to cardiovascular disease (CVD) mortality and to all-cause mortality within strata of other personal characteristics that predispose to early mortality. DESIGN--Observational cohort study. We calculated CVD and all-cause death rates for low (least fit 20%), moderate (next 40%), and high (most fit 40%) fitness categories by strata of smoking habit, cholesterol level, blood pressure, and health status. Preventive medicine clinic. Participants were 25341 men and 7080 women who completed preventive medical examinations, including a maximal exercise test. Cardiovascular disease and all-cause mortality. There were 601 deaths during 211996 man-years of follow-up, and 89 deaths during 52982 woman-years of follow-up. Independent predictors of mortality among men, with adjusted relative risks (RRs) and 95% confidence intervals (CIs), were low fitness (RR, 1.52;95% CI, 1.28-1.82), smoking (RR, 1.65; 95% CI, 1.39-1.97), abnormal electrocardiogram (RR, 1.64;95% CI, 1.34-2.01), chronic illness (RR, 1.63;95% CI, 1.37-1.95), increased cholesterol level (RR, 1.34; 95% CI, 1.13-1.59), and elevated systolic blood pressure (RR, 1.34; 95% CI, 1.13-1.59). The only statistically significant independent predictors of mortality in women were low fitness (RR, 2.10; 95% Cl, 1.36-3.21) and smoking (RR, 1.99; 95% Cl, 1.25-3.17). Inverse gradients were seen for mortality across fitness categories within strata of other mortality predictors for both sexes. Fit persons with any combination of smoking, elevated blood pressure, or elevated cholesterol level had lower adjusted death rates than low-fit persons with none of these characteristics. Low fitness is an important precursor of mortality. The protective effect of fitness held for smokers and nonsmokers, those with and without elevated cholesterol levels or elevated blood pressure, and unhealthy and healthy persons. Moderate fitness seems to protect against the influence of these other predictors on mortality. Physicians should encourage sedentary patients to become physically active and thereby reduce the risk of premature mortality.
          Article 0 comments Cited 226 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Aerobic endurance training improves soccer performance.

            J Helgerud, L C Engen, U Wisloff … (2001)
            The aim of the present study was to study the effects of aerobic training on performance during soccer match and soccer specific tests. Nineteen male elite junior soccer players, age 18.1 +/- 0.8 yr, randomly assigned to the training group (N = 9) and the control group (N = 10) participated in the study. The specific aerobic training consisted of interval training, four times 4 min at 90-95% of maximal heart rate, with a 3-min jog in between, twice per week for 8 wk. Players were monitored by video during two matches, one before and one after training. In the training group: a) maximal oxygen uptake (VO2max) increased from 58.1 +/- 4.5 mL x kg(-1) x min(-1) to 64.3 +/- 3.9 mL x kg(-1) x min(-1) (P < 0.01); b) lactate threshold improved from 47.8 +/- 5.3 mL x kg(-1) x min(-1) to 55.4 +/- 4.1 mL x kg(-1) x min(-1) (P < 0.01); c) running economy was also improved by 6.7% (P < 0.05); d) distance covered during a match increased by 20% in the training group (P < 0.01); e) number of sprints increased by 100% (P < 0.01); f) number of involvements with the ball increased by 24% (P < 0.05); g) the average work intensity during a soccer match, measured as percent of maximal heart rate, was enhanced from 82.7 +/- 3.4% to 85.6 +/- 3.1% (P < 0.05); and h) no changes were found in maximal vertical jumping height, strength, speed, kicking velocity, kicking precision, or quality of passes after the training period. The control group showed no changes in any of the tested parameters. Enhanced aerobic endurance in soccer players improved soccer performance by increasing the distance covered, enhancing work intensity, and increasing the number of sprints and involvements with the ball during a match.
            Article 0 comments Cited 189 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.

              L Mishra, B. B. Singh, S Dagenais (2000)
              The objective of this paper is to review the literature regarding Withania somnifera (ashwagandha, WS) a commonly used herb in Ayurvedic medicine. Specifically, the literature was reviewed for articles pertaining to chemical properties, therapeutic benefits, and toxicity. This review is in a narrative format and consists of all publications relevant to ashwagandha that were identified by the authors through a systematic search of major computerized medical databases; no statistical pooling of results or evaluation of the quality of the studies was performed due to the widely different methods employed by each study. Studies indicate ashwagandha possesses anti-inflammatory, antitumor, antistress, antioxidant, immunomodulatory, hemopoietic, and rejuvenating properties. It also appears to exert a positive influence on the endocrine, cardiopulmonary, and central nervous systems. The mechanisms of action for these properties are not fully understood. Toxicity studies reveal that ashwagandha appears to be a safe compound. Preliminary studies have found various constituents of ashwagandha exhibit a variety of therapeutic effects with little or no associated toxicity. These results are very encouraging and indicate this herb should be studied more extensively to confirm these results and reveal other potential therapeutic effects. Clinical trials using ashwagandha for a variety of conditions should also be conducted.
              Article 0 comments Cited 143 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Nutrients
                Journal ID (iso-abbrev): Nutrients
                Journal ID (publisher-id): nutrients
                Title: Nutrients
                Publisher: MDPI
                ISSN (Electronic): 2072-6643
                Publication date (Electronic): 17 April 2020
                Publication date Collection: April 2020
                Volume: 12
                Issue: 4
                Electronic Location Identifier: 1119
                Affiliations
                [1 ]HEME Research Group, Faculty of Sport Sciences, University of Extremadura, 10003 Caceres, Spain; jorgepg100@ 123456gmail.com (J.P.-G.);
                [2 ]Physical Activity and Quality of Life Research Group (AFYCAV), Faculty of Sport Science, University of Extremadura, 10003 Cáceres, Spain
                [3 ]Facultad de Educación, Universidad Autónoma de Chile, Talca 3460000, Chile; emerellano@ 123456gmail.com
                [4 ]Centre for Sport Studies, Rey Juan Carlos University, Fuenlabrada, 28943 Madrid, Spain; danicolladom@ 123456gmail.com
                Author notes
                [* ]Correspondence: svillafaina@ 123456unex.es ; Tel.: +34-927-257-460
                Author information
                https://orcid.org/0000-0002-4054-9132
                https://orcid.org/0000-0003-0784-1753
                https://orcid.org/0000-0001-7203-3168
                https://orcid.org/0000-0002-1557-2285
                https://orcid.org/0000-0002-5140-465X
                Article
                Publisher ID: nutrients-12-01119
                DOI: 10.3390/nu12041119
                PMC ID: 7230697
                PubMed ID: 32316411
                SO-VID: a6849868-c7fe-43f7-836c-2a5654346cac
                Copyright © © 2020 by the authors.
                License:

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                Date received : 15 March 2020
                Date accepted : 14 April 2020
                Categories
                Subject: Communication

                ScienceOpen disciplines: Nutrition & Dietetics
                Keywords: ergogenic aids,maximum oxygen consumption,performance sports,physical fitness
                Data availability:
                ScienceOpen disciplines: Nutrition & Dietetics
                Keywords: ergogenic aids, maximum oxygen consumption, performance sports, physical fitness

                Comments

                Comment on this article

                scite_

                Similar content896

                See all similar

                Cited by7

                See all cited by

                Most referenced authors831

                See all reference authors