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      Hemolytic uremic syndrome due to an altered factor H triggered by neonatal pertussis.

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          Abstract

          We report on a previously healthy newborn suffering from severe Bordetella pertussis infection who developed hemolytic uremic syndrome (HUS) a few weeks after the onset of whooping cough, with a fatal outcome. A factor H protein with abnormal mobility was found in the serum of the patient as analyzed by Western blotting, indicating that B. pertussis infection might have triggered HUS in a genetically predisposed patient.

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          Author and article information

          Journal
          Pediatr. Nephrol.
          Pediatric nephrology (Berlin, Germany)
          Springer Nature
          0931-041X
          0931-041X
          Mar 2002
          : 17
          : 3
          Affiliations
          [1 ] University Children's Hospital, Mathildenstrasse 1, 79106 Freiburg, Germany. berner@kikli.ukl.uni-freiburg.de
          Article
          10.1007/s00467-001-0798-6
          11956859
          a6ab5249-91f5-40e4-b07e-aacb800a3d26
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