Muhamuda Kader:
ORCID: http://orcid.org/0000-0001-8902-9296
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: SoftwareRole: SupervisionRole: ValidationRole: Writing – original
draftRole: Writing – review & editing
Mounia Alaoui-EL-Azher:
ORCID: http://orcid.org/0000-0002-3209-5257
Role: ConceptualizationRole: Data curationRole: MethodologyRole: Writing – original
draft
Jennie Vorhauer:
ORCID: http://orcid.org/0000-0002-3897-6354
Role: Data curationRole: Formal analysisRole: Writing – review & editing
Bhushan B Kode: Role: Data curationRole: Methodology
Jakob Z. Wells:
ORCID: http://orcid.org/0000-0003-3530-8593
Role: Data curationRole: Formal analysisRole: Methodology
Donna Stolz:
ORCID: http://orcid.org/0000-0002-1833-7010
Role: Funding acquisitionRole: MethodologyRole: ResourcesRole: SoftwareRole: Visualization
George Michalopoulos: Role: Funding acquisitionRole: InvestigationRole: ResourcesRole: Supervision
Alan Wells:
ORCID: http://orcid.org/0000-0002-1637-8150
Role: Funding acquisitionRole: InvestigationRole: ResourcesRole: Writing – review
& editing
Melanie Scott:
ORCID: http://orcid.org/0000-0001-6864-5970
Role: ConceptualizationRole: Formal analysisRole: Funding acquisitionRole: MethodologyRole:
Writing – original draftRole: Writing – review & editing
Nahed Ismail: Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
InvestigationRole: MethodologyRole: Project administrationRole: ResourcesRole: SoftwareRole:
SupervisionRole: ValidationRole: VisualizationRole: Writing – original draftRole:
Writing – review & editing
Jorn Coers: Role: Editor
Journal ID (nlm-ta): PLoS Pathog
Journal ID (iso-abbrev): PLoS Pathog
Journal ID (publisher-id): plos
Journal ID (pmc): plospath
Title:
PLoS Pathogens
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-7366
ISSN
(Electronic):
1553-7374
Publication date
(Electronic):
19
October
2017
Publication date Collection:
October
2017
Volume: 13
Issue: 10
Electronic Location Identifier: e1006644
Affiliations
[1
]
Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United
States of America
[2
]
Center for Biologic Imaging, University of Pittsburgh Medical School, Pittsburgh,
Pennsylvania, United States of America
[3
]
Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania,
United States of America
[4
]
Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United
States of America
[5
]
Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, United
States of America
Author notes
The authors have declared that no competing interests exists.
‡ These authors are co-senior authors on this work.
Author information
Article
Publisher ID:
PPATHOGENS-D-17-00878
DOI: 10.1371/journal.ppat.1006644
PMC ID: 5663626
PubMed ID: 29049365
SO-VID: a6e62fd1-f300-42b7-899e-56d104f76a9e
Copyright © © 2017 Kader et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/100000054, National Cancer Institute;
Award ID: NCI-UH3TR000496
Award Recipient
:
ORCID: http://orcid.org/0000-0002-1637-8150
Alan Wells
Funded by: funder-id http://dx.doi.org/10.13039/100000057, National Institute of General Medical Sciences;
Award ID: NIGMS:R01-GM102146
Award Recipient
:
ORCID: http://orcid.org/0000-0001-6864-5970
Melanie Scott
Funded by: funder-id http://dx.doi.org/10.13039/100000060, National Institute of Allergy and Infectious Diseases;
Award ID: NIAID-R56AI097679-01A
Award Recipient
:
Nahed Ismail
This work was funded by the National Cancer Institute grant number NCI-UH3TR000496
(AW), National Institute of General Medical Sciences grant number NIGMS-RO1-GM102146
(MS), National Institute of Allergy and Infectious Diseases grant number NIAID-R56A1097679-01A
(NI). The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Inflammasomes
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Inflammasomes
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Immune System Proteins
Subject:
Inflammasomes
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Ehrlichia
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Ehrlichia
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Bacteria
Subject:
Rickettsiales
Subject:
Ehrlichia
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cell Processes
Subject:
Cell Death
Subject:
Autophagic Cell Death
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
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Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Bioenergetics
Subject:
Energy-Producing Organelles
Subject:
Mitochondria
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Structures and Organelles
Subject:
Energy-Producing Organelles
Subject:
Mitochondria
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Molecular Probe Techniques
Subject:
Immunoblotting
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Molecular Probe Techniques
Subject:
Immunoblotting
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Intracellular Pathogens
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
T Cells
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
T Cells
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
T Cells
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
T Cells