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Abstract
In an attempt to determine whether Trypanosoma congolense occurs both within and outside
the blood vessels in an infected animal host, multimammate rats (Mastomys coucha)
were infected with T. congolense and samples from spleen, lymph nodes, bone marrow,
liver, kidney, lungs, brain, heart, intestines, ovaries and testes were collected.
The tissue samples were fixed and processed for light and electron microscopical examination.
In all the tissues examined, trypanosomes were found only within the lumen of large
and small blood vessels, capillaries and sinuses. It is concluded that following entry
into the blood circulation after intra-peritoneal infection of M. coucha, T. congolense
remains restricted to the bloodstream.