Patrick James Berkeley Walker , 1 , 2 , Ayobami Adebayo Bakare 3 , 4 , Adejumoke Idowu Ayede 3 , Rosena Olubanke Oluwafemi 5 , Omolayo Adebukola Olubosede 6 , Iyabo Victoria Olafimihan 7 , Kenneth Tan 8 , 9 , Trevor Duke 10 , 11 , Adegoke Gbadegesin Falade 12 , 13 , Hamish Graham 14
28 August 2019
To evaluate the effectiveness of intermittent pulse oximetry in guiding oxygen therapy in neonates in a low-resource setting.
Prospective validation study at three hospitals in southwest Nigeria. We performed concealed continuous pulse oximetry on participants to evaluate intermittent SpO 2 monitoring.
We recruited all preterm or low birthweight neonates, and all term neonates who required oxygen therapy, who were admitted to the neonatal ward(s) of the study hospitals during the study period.
Proportion of time preterm/low birthweight neonates on oxygen spent within, above and below the target SpO 2 range of 90%–95%; and the proportion of time term neonates and neonates not on oxygen spent within and below the target range of 90%–100%.
Preterm/low birthweight neonates receiving oxygen therapy (group A) spent 15.7% (95% CI 13.3 to 18.9) of time in the target SpO 2 range of 90%–95%. They spent 75.0% (63.6–81.1) of time above 95%, and 2.7% (1.7–5.6) of time below 85%. Term neonates and all neonates not receiving oxygen (group B) spent 97.3% (95% CI 96.4 to 98.6) of time within the target range of 90%–100%, and 0.9% (0.3–1.4) of time below 85%. Guidelines recommended SpO 2 monitoring 3 times per day for all patients, however neonates in groups A and B were monitored an average of 4.7 and 5.3 times per day, respectively.