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      Spontaneous pneumothorax in a single lung transplant recipient-a blessing in disguise: A case report

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          Abstract

          BACKGROUND

          End-stage chronic obstructive pulmonary disease (COPD) is one of the common lung diseases referred for lung transplantation. According to the international society of heart and lung transplantation, 30% of all lung transplantations are carried out for COPD alone. When compared to bilateral lung transplant, single-lung transplant (SLT) has similar short-term and medium-term results for COPD. For patients with severe upper lobe predominant emphysema, lung volume reduction surgery is an excellent alternative which results in improvement in functional status and long-term mortality. In 2018, endobronchial valves were approved by the Food and Drug Administration for severe upper lobe predominant emphysema as they demonstrated improvement in lung function, exercise capacity, and quality of life. However, the role of endobronchial valves in native lung emphysema in SLT patients has not been studied.

          CASE SUMMARY

          We describe an unusual case of severe emphysema who underwent a successful SLT 15 years ago and had gradual worsening of lung function suggestive of chronic lung allograft dysfunction. However, her lung function improved significantly after a spontaneous pneumothorax of the native lung resulting in auto-deflation of large bullae.

          CONCLUSION

          This case highlights the clinical significance of native lung hyperinflation in single lung transplant recipient and how spontaneous decompression due to pneumothorax led to clinical improvement in our patient.

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          Most cited references19

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          International guidelines for the selection of lung transplant candidates: 2006 update--a consensus report from the Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation.

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            The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-Fifth Adult Lung and Heart–Lung Transplant Report—2018; Focus Theme: Multiorgan Transplantation

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              Endobronchial Valve Therapy in Patients with Homogeneous Emphysema. Results from the IMPACT Study.

              Endobronchial valves (EBVs) have been successfully used in patients with severe heterogeneous emphysema to improve lung physiology. Limited available data suggest that EBVs are also effective in homogeneous emphysema.
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                Author and article information

                Contributors
                Journal
                World J Clin Cases
                WJCC
                World Journal of Clinical Cases
                Baishideng Publishing Group Inc
                2307-8960
                26 July 2020
                26 July 2020
                : 8
                : 14
                : 3031-3038
                Affiliations
                Division of Pulmonary, Critical Care and Sleep Medicine, New York University Grossman School of Medicine, New York, NY 10016, United States
                Imaging Institute, Section of Thoracic Imaging, Cleveland Clinic, Cleveland, OH 44195, United States. ghoshs2@ 123456ccf.org
                Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, United States
                Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, United States
                Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, United States
                Respiratory Institute, Cleveland Clinic, Cleveland, OH 44195, United States
                Author notes

                Author contributions: Deshwal H and Mehta AC reviewed the literature and drafted the manuscript; Ghosh S interpreted the imaging findings and drafted the manuscript; Hogan K obtained patient consent and reviewed the manuscript; Akindipe O and Lane CR reviewed and edited the manuscript; Deshwal H, Ghosh S and Mehta AC were responsible for the revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.

                Corresponding author: Subha Ghosh, MD, MBA; Assistant Professor, Staff Physician, Imaging Institute, Section of Thoracic Imaging, Cleveland Clinic, 9500 Euclid Avenue, L/10, Cleveland, OH 44195, United States. ghoshs2@ 123456ccf.org

                Article
                jWJCC.v8.i14.pg3031
                10.12998/wjcc.v8.i14.3031
                7385599
                a7b59d6a-eac7-4a83-8ec3-7c51eb14a665
                ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

                This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

                History
                : 19 March 2020
                : 25 May 2020
                : 16 July 2020
                Categories
                Case Report

                native lung hyperinflation,single lung transplant,pneumothorax,bronchoscopic lung volume reduction,endobronchial valve,case report

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