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      Left ventrolateral prefrontal cortex and the cognitive control of memory.

      1 ,
      Neuropsychologia
      Elsevier BV

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          Abstract

          Cognitive control mechanisms permit memory to be accessed strategically, and so aid in bringing knowledge to mind that is relevant to current goals and actions. In this review, we consider the contribution of left ventrolateral prefrontal cortex (VLPFC) to the cognitive control of memory. Reviewed evidence supports a two-process model of mnemonic control, supported by a double dissociation among rostral regions of left VLPFC. Specifically, anterior VLPFC (approximately BA 47; inferior frontal gyrus pars orbitalis) supports controlled access to stored conceptual representations, whereas mid-VLPFC (approximately BA 45; inferior frontal gyrus pars triangularis) supports a domain-general selection process that operates post-retrieval to resolve competition among active representations. We discuss the contribution of these control mechanisms across a range of mnemonic domains, including semantic retrieval, recollection of contextual details about past events, resolution of proactive interference in working memory, and task switching. Finally, we consider open directions for future research into left VLPFC function and the cognitive control of memory.

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          Author and article information

          Journal
          Neuropsychologia
          Neuropsychologia
          Elsevier BV
          0028-3932
          0028-3932
          Oct 01 2007
          : 45
          : 13
          Affiliations
          [1 ] Helen Wills Neuroscience Institute, 132 Barker Hall, MC3190, UC Berkeley, CA 94720-3190, USA. dbadre@berkeley.edu
          Article
          S0028-3932(07)00221-7
          10.1016/j.neuropsychologia.2007.06.015
          17675110
          a7c2fe0e-bbe6-4d85-8ec8-154934b5c883
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