Positron emission tomography (PET) is a powerful noninvasive imaging tool for phenotyping
patients at risk of or with known coronary artery disease (CAD). One of the key advantages
over other imaging modalities is its unique ability to quantify physiologic processes,
including myocardial blood flow (in milliliters per minute per gram of myocardium),
metabolism, and cardiac receptors, and its high sensitivity for delineating and quantifying
molecular targets in vivo using targeted imaging probes. Cardiac PET/CT offers opportunity
for a comprehensive noninvasive evaluation of the consequences of atherosclerosis
in the coronary arteries and the myocardium.