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      Cardiac PET/CT and Prognosis

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          Abstract

          Positron emission tomography (PET) is a powerful noninvasive imaging tool for phenotyping patients at risk of or with known coronary artery disease (CAD). One of the key advantages over other imaging modalities is its unique ability to quantify physiologic processes, including myocardial blood flow (in milliliters per minute per gram of myocardium), metabolism, and cardiac receptors, and its high sensitivity for delineating and quantifying molecular targets in vivo using targeted imaging probes. Cardiac PET/CT offers opportunity for a comprehensive noninvasive evaluation of the consequences of atherosclerosis in the coronary arteries and the myocardium.

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          Most cited references 43

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          Determinants of the response of left ventricular ejection fraction to vasodilator stress in electrocardiographically gated 82rubidium myocardial perfusion PET

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            Relationship between CT coronary angiography and stress perfusion imaging in patients with suspected ischemic heart disease assessed by integrated PET-CT imaging

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              Physiological basis for angina and ST-segment change PET-verified thresholds of quantitative stress myocardial perfusion and coronary flow reserve

               NP Johnson,  KL Gould (2011)
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                Author and article information

                Journal
                CVIA
                Cardiovascular Innovations and Applications
                CVIA
                Compuscript (Ireland )
                2009-8782
                2009-8618
                December 2016
                March 2017
                : 2
                : 1
                : 47-59
                Affiliations
                1Cardiovascular Imaging Program, Departments of Radiology and Medicine, the Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, and the Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
                Author notes
                Correspondence: Marcelo F. Di Carli, MD, Brigham and Women's Hospital, ASB L1 037-C, 75 Francis St., Boston, MA 02115, USA, Tel.: (617) 732-6291; Fax: (617) 582-6056, E-mail: mdicarli@ 123456partners.org
                Article
                cvia20160046
                10.15212/CVIA.2016.0046
                Copyright © 2017 Cardiovascular Innovations and Applications

                This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.

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