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Cardiac PET/CT and Prognosis

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      Abstract

      Positron emission tomography (PET) is a powerful noninvasive imaging tool for phenotyping patients at risk of or with known coronary artery disease (CAD). One of the key advantages over other imaging modalities is its unique ability to quantify physiologic processes, including myocardial blood flow (in milliliters per minute per gram of myocardium), metabolism, and cardiac receptors, and its high sensitivity for delineating and quantifying molecular targets in vivo using targeted imaging probes. Cardiac PET/CT offers opportunity for a comprehensive noninvasive evaluation of the consequences of atherosclerosis in the coronary arteries and the myocardium.

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      Most cited references 43

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      Relationship between stress-induced myocardial ischemia and atherosclerosis measured by coronary calcium tomography

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        Prediction of short-term cardiovascular events using quantification of global myocardial flow reserve in patients referred for clinical 82Rb PET perfusion imaging

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          Quantitative assessment of myocardial perfusion in the detection of significant coronary artery disease: cutoff values and diagnostic accuracy of quantitative [15O]H2O PET imaging

           I Danad,  V Uusitalo,  T Kero (2014)
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            Author and article information

            Affiliations
            1Cardiovascular Imaging Program, Departments of Radiology and Medicine, the Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, and the Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
            Author notes
            Correspondence: Marcelo F. Di Carli, MD, Brigham and Women's Hospital, ASB L1 037-C, 75 Francis St., Boston, MA 02115, USA, Tel.: (617) 732-6291; Fax: (617) 582-6056, E-mail: mdicarli@123456partners.org
            Journal
            CVIA
            Cardiovascular Innovations and Applications
            CVIA
            Compuscript (Ireland)
            2009-8782
            2009-8618
            December 2016
            March 2017
            : 2
            : 1
            : 47-59
            Copyright © 2017 Cardiovascular Innovations and Applications

            This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.

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