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      Carbon Nanotropes: A Contemporary Paradigm in Drug Delivery

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          Abstract

          Discovery of fullerenes and other nanosized carbon allotropes has opened a vast new field of possibilities in nanotechnology and has become one of the most promising research areas. Carbon nanomaterials have drawn interest as carriers of biologically pertinent molecules due to their distinctive physical, chemical and physiological properties. We have assigned the nomenclature “Carbon Nanotropes” to the nanosized carbon allotropes. Carbon nanotropes such as fullerenes, carbon nanotubes (CNTs) and graphenes, have exhibited wide applicability in drug delivery, owing to their small size and biological activity. The nanotherapeutics/diagnostics will allow a deeper understanding of human ills including cancer, neurodegenerative diseases, genetic disorders and various other complications. Recently, nanomaterials with multiple functions, such as drug carrier, MRI, optical imaging, photothermal therapy, etc., have become more and more popular in the domain of cancer and other areas of research. This review is an endeavor to bring together the usefulness of the carbon nanomaterials in the field of drug delivery. The last section of the review encompasses the recent patents granted on carbon nanotropes at United State Patent Trademark Office (USPTO) in the related field.

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          Most cited references133

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          Electric Field Effect in Atomically Thin Carbon Films

          We report a naturally-occurring two-dimensional material (graphene that can be viewed as a gigantic flat fullerene molecule, describe its electronic properties and demonstrate all-metallic field-effect transistor, which uniquely exhibits ballistic transport at submicron distances even at room temperature.
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            Strength and Breaking Mechanism of Multiwalled Carbon Nanotubes Under Tensile Load

            M Yu (2000)
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              Carbon-based electronics.

              The semiconductor industry has been able to improve the performance of electronic systems for more than four decades by making ever-smaller devices. However, this approach will soon encounter both scientific and technical limits, which is why the industry is exploring a number of alternative device technologies. Here we review the progress that has been made with carbon nanotubes and, more recently, graphene layers and nanoribbons. Field-effect transistors based on semiconductor nanotubes and graphene nanoribbons have already been demonstrated, and metallic nanotubes could be used as high-performance interconnects. Moreover, owing to the excellent optical properties of nanotubes it could be possible to make both electronic and optoelectronic devices from the same material.
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                Author and article information

                Contributors
                Role: Academic Editor
                Journal
                Materials (Basel)
                Materials (Basel)
                materials
                Materials
                MDPI
                1996-1944
                29 May 2015
                June 2015
                : 8
                : 6
                : 3068-3100
                Affiliations
                [1 ]Division of Pharmaceutical Chemistry, Faculty of Pharmacy, Babu Banarasi Das Northern India Institute of Technology, BBD City, Faizabad Road, Chinhut, Lucknow 226028, U.P., India; E-Mail: aviniec31@ 123456gmail.com
                [2 ]Department of Pharmaceutical Sciences, Babasaheb Bhimrao Ambedkar University, Lucknow 226025, U.P., India; E-Mail: shubhini.saraf@ 123456gmail.com
                Author notes
                [* ] Author to whom correstpondence should be addressed; E-Mail: dirpharmniec@ 123456gmail.com ; Tel.: +91-522-3911052; Fax: +91-522-3911152.
                Article
                materials-08-03068
                10.3390/ma8063068
                5455721
                a7f11596-4dae-4be6-b9bb-028e750600bd
                © 2015 by the authors;

                licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 06 February 2015
                : 22 May 2015
                Categories
                Review

                nanomaterials,carbon allotroptes,toxicity of carbon nanomaterials,cnts,fullerenes,graphenes,drug delivery systems,anticancer drug delivery,delivery of biomoleculses,biosensors

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