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      Malignant Female Adnexal Tumor of Probable Wolffian Origin: Case Report and Literature Review.

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          Abstract

          Although most female adnexal tumors of probable Wolffian origin have a benign biologic behavior, occasional cases have exhibited malignant potential. We encountered a 50-yr-old woman with an uncommon female adnexal tumors of probable Wolffian origin, which involved bilateral ovaries, invaded the ipsilateral fallopian tube, and extended to the uterine serosa. The initial histopathologic presentation caused significant confusion in pathologic diagnosis. Multiple differential diagnoses including ovarian endometrioid carcinoma, Sertoli cell tumor, and metastasis from nongynecologic organs were considered. After careful examination of the histologic findings and a thorough investigation with multiple immunohistochemical stains, the diagnosis was ultimately established. A literature review on female adnexal tumors of probable Wolffian origin including a malignant form is presented.

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          Author and article information

          Journal
          Int. J. Gynecol. Pathol.
          International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
          Ovid Technologies (Wolters Kluwer Health)
          1538-7151
          0277-1691
          Jul 2018
          : 37
          : 4
          Affiliations
          [1 ] Departments of Gynecology (S.H.) Pathology (J.C.), Shandong Provincial Qianfoshan Hospital Department of Pathology, School of Medicine (L.L.), Shandong University, Jinan, Shandong, China Arizona Oncology Associates, Tucson, Arizona (J.B., C.L.) Departments of Pathology (S.H., J.C., L.L., W.Z.) Obstetrics and Gynecology (W.Z.), University of Texas Southwestern Medical Center Harold C. Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center (W.Z.), Dallas, Texas.
          Article
          10.1097/PGP.0000000000000422
          28700436
          a876f851-53f0-407f-a224-c4a14b0e59da
          History

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