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      • Record: found
      • Abstract: found
      • Article: found

      Life Span of Human Corneal Endothelial Cells in Long-Term Cultures

      research-article
      Author(s): a , b , a
      Publication date (Electronic):
      Journal: Ophthalmic Research
      Publisher: S. Karger AG
      Keywords: Cornea, Human endothelial cells, Life span

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          Abstract

          Human corneal endothelial cells (HCEC) were isolated from excised corneas of adult donors in the age range of 28–70 years, and successfully grown for 10–12 passages. Moreover, one cell line, that had been established from a 45-year-old donor, was further passaged at defined split ratios in order to determine the proliferative life span of the HCEC isolated from donors of this age group.

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          Author and article information

          Journal
          Journal ID (publisher-id): ORE
          Journal ID (nlm-ta): Ophthalmic Res
          Journal ID (doi): 10.1159/issn.0030-3747
          Title: Ophthalmic Research
          Publisher: S. Karger AG
          ISSN (Print): 0030-3747
          ISSN (Electronic): 1423-0259
          Publication date Subscription-year: 1989
          Publication date (Print): 1989
          Publication date (Electronic): 10 December 2009
          Volume: 21
          Issue: 4
          Pages: 303-308
          Affiliations
          aAbteilung Cytogenetik, GBF – Gesellschaft für Biotechnologische Forschung mbH, Braunschweig; bUniversitätskrankenhaus Hamburg-Eppendorf, Augenklinik, Hamburg, BRD
          Article
          Publisher ID: 266874 Other ID: Ophthalmic Res 1989;21:303–308
          DOI: 10.1159/000266874
          PubMed ID: 2587015
          SO-VID: a895b05e-30c5-4781-b7be-c16c8850ed5a
          Copyright © © 1989 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Date received : 12 July 1988
          Date accepted : 19 October 1988
          Page count
          Pages: 6
          Categories
          Subject: Original Paper

          ScienceOpen disciplines: Vision sciences,Ophthalmology & Optometry,Pathology
          Keywords: Cornea,Human endothelial cells,Life span
          Data availability:
          ScienceOpen disciplines: Vision sciences, Ophthalmology & Optometry, Pathology
          Keywords: Cornea, Human endothelial cells, Life span

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