Electrophysiologic effects of the new class III antiarrhythmic drug dofetilide compared to the class IA antiarrhythmic drug quinidine in experimental canine atrial flutter: role of dispersion of refractoriness in antiarrhythmic efficacy.

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Abstract

Previous studies suggest that class III antiarrhythmic drugs are more effective in reentrant arrhythmias because they prolong refractoriness (ERP) and wavelength and reduce dispersion of refractoriness compared to Class IA antiarrhythmic drugs, which slow conduction velocity (CV) in addition to their effects on refractoriness.

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Journal

Journal ID (iso-abbrev): J. Cardiovasc. Electrophysiol.

Title: Journal of cardiovascular electrophysiology

Publisher: Wiley

ISSN: 1045-3873

ISSN (Print): 1045-3873

Publication date (Electronic): Sep 1996

Volume: 7

Issue: 9

Affiliations

[1 ] Division of Cardiology, University of California, San Diego 92103, USA.

Article

DOI: 10.1111/j.1540-8167.1996.tb00594.x

PubMed ID: 8884510

SO-VID: a9695a2e-c1b5-4e03-9404-b27a5efe7e4e

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