Blog
About

  • Record: found
  • Abstract: found
  • Article: not found

Tolerance of normal tissue to therapeutic irradiation.

International Journal of Radiation Oncology, Biology, Physics

radiation effects, Brain, Humans, Kidney, Lung, Bone and Bones, Neoplasms, radiotherapy, Radiation Dosage, Radiation Tolerance, Radiotherapy Planning, Computer-Assisted, Spinal Cord, Thyroid Gland

Read this article at

ScienceOpenPubMed
Bookmark
      There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

      Abstract

      The importance of knowledge on tolerance of normal tissue organs to irradiation by radiation oncologists cannot be overemphasized. Unfortunately, current knowledge is less than adequate. With the increasing use of 3-D treatment planning and dose delivery, this issue, particularly volumetric information, will become even more critical. As a part of the NCI contract N01 CM-47316, a task force, chaired by the primary author, was formed and an extensive literature search was carried out to address this issue. In this issue. In this manuscript we present the updated information on tolerance of normal tissues of concern in the protocols of this contract, based on available data, with a special emphasis on partial volume effects. Due to a lack of precise and comprehensive data base, opinions and experience of the clinicians from four universities involved in the contract have also been contributory. Obviously, this is not and cannot be a comprehensive work, which is beyond the scope of this contract.

      Related collections

      Author and article information

      Journal
      2032882

      Comments

      Comment on this article