Blog
About

  • Record: found
  • Abstract: found
  • Article: not found

AA-amyloidosis in dogs: partial amino acid sequence of protein AA and immunohistochemical cross-reactivity with human and cow AA-amyloid.

Comparative biochemistry and physiology. B, Comparative biochemistry

Species Specificity, Amino Acid Sequence, Amyloid, isolation & purification, Amyloidosis, metabolism, pathology, veterinary, Animals, Cattle, Cattle Diseases, Dog Diseases, Dogs, Humans, Kidney, Serum Amyloid A Protein

Read this article at

ScienceOpenPubMed
Bookmark
      There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

      Abstract

      Protein AA was purified from the kidneys of dogs with spontaneous reactive amyloidosis. The protein had a blocked N-terminal. Sequence analysis of a peptide obtained after cyanogen bromide cleavage revealed an amino acid sequence corresponding to positions 24-42 of human AA. This region showed a strong homology to protein AA of other species. Antiserum to both human and dog protein AA reacted immunohistochemically with AA amyloid of human, dog and cow origin.

      Related collections

      Author and article information

      Journal
      4053581

      Comments

      Comment on this article