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Major Outcomes in High-Risk Hypertensive Patients Randomized to Angiotensin-Converting Enzyme Inhibitor or Calcium Channel Blocker vs Diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
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Abstract
Antihypertensive therapy is well established to reduce hypertension-related morbidity
and mortality, but the optimal first-step therapy is unknown.