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      Non-Hodgkin lymphoma.

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          Abstract

          Lymphomas can affect any organ in the body, present with a wide range of symptoms, and be seen by primary care physicians and physicians from most specialties. They are traditionally divided into Hodgkin's lymphoma (which accounts for about 10% of all lymphomas) and non-Hodgkin lymphoma, which is the topic of this Seminar. Non-Hodgkin lymphoma represents a wide spectrum of illnesses that vary from the most indolent to the most aggressive malignancies. They arise from lymphocytes that are at various stages of development, and the characteristics of the specific lymphoma subtype reflect those of the cell from which they originated. Since this topic was last reviewed in The Lancet in 2012, advances in understanding the biology and genetics of non-Hodgkin lymphoma and the availability of new diagnostic methods and therapies have improved our ability to manage patients with this disorder.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          1474-547X
          0140-6736
          July 15 2017
          : 390
          : 10091
          Affiliations
          [1 ] University of Nebraska Medical Center, Omaha, NE, USA. Electronic address: joarmita@unmc.edu.
          [2 ] British Columbia Cancer Agency and British Columbia Cancer Research Centre, Vancouver, BC, Canada.
          [3 ] University of Nebraska Medical Center, Omaha, NE, USA.
          [4 ] Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
          Article
          S0140-6736(16)32407-2
          10.1016/S0140-6736(16)32407-2
          28153383
          a9eff27a-d18d-4f43-9c37-518de68477bd
          Copyright © 2017 Elsevier Ltd. All rights reserved.
          History

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