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      Anti-inflammatory properties of Lipidosterolic extract of Serenoa repens (Permixon®) in a mouse model of prostate hyperplasia.

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          Abstract

          Permixon®, the hexanic lipidosterolic extract of saw palmetto Serenoa repens (LSESr), has shown properties that highlight its benefit in the management of benign prostate hyperplasia (BPH). To address its actual anti-inflammatory potency, we used a unique pro-inflammatory mouse model of prostate hyperplasia involving prostate-specific over-expression of prolactin transgene (Pb-Prl).

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          Author and article information

          Journal
          Prostate
          The Prostate
          1097-0045
          0270-4137
          May 2015
          : 75
          : 7
          Affiliations
          [1 ] Inserm U1151, Université Paris Descartes, Paris, France.
          Article
          10.1002/pros.22953
          25683150
          aa01fb4d-edda-48da-9376-eba2f6f4ccd5
          © 2015 Wiley Periodicals, Inc.
          History

          BPH,IL-17,IL-6,LSESr,inflammation,mouse model
          BPH, IL-17, IL-6, LSESr, inflammation, mouse model

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