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      Tracer uptake in mediastinal and paraaortal thoracic lymph nodes as a potential pitfall in image interpretation of PSMA ligand PET/CT.

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          Abstract

          Since the introduction of 68Ga-PSMA-11 PET/CT for imaging prostate cancer (PC) we have frequently observed mediastinal lymph nodes (LN) showing tracer uptake despite being classified as benign. The aim of this evaluation was to further analyze such LN.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Eur. J. Nucl. Med. Mol. Imaging
          Title: European journal of nuclear medicine and molecular imaging
          Publisher: Springer Nature America, Inc
          ISSN (Electronic): 1619-7089
          ISSN (Print): 1619-7070
          Publication date (Electronic): July 2018
          Volume: 45
          Issue: 7
          Affiliations
          [1 ] Department of Nuclear Medicine, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany. a.afshar@gmx.de.
          [2 ] Department of Nuclear Medicine, Bern University Hospital (Inselspital), Bern, Switzerland. a.afshar@gmx.de.
          [3 ] Department of Nuclear Medicine, Heidelberg University Hospital, INF 400, 69120, Heidelberg, Germany.
          [4 ] Institute of Pathology, Technical University of Munich, Munich, Germany.
          [5 ] Department of Biostatistics, German Cancer Research Center, Heidelberg, Germany.
          [6 ] Department of Nuclear Medicine, Hospital Israelita Albert-Einstein, São Paulo, Brazil.
          [7 ] Division of Radiopharmaceutical Chemistry, German Cancer Research Center, Heidelberg, Germany.
          [8 ] German Cancer Consortium (DKTK), Heidelberg, Germany.
          [9 ] German Cancer Consortium (DKTK), Munich, Germany.
          [10 ] Department of Nuclear Medicine, Bern University Hospital (Inselspital), Bern, Switzerland.
          Article
          Publisher Item ID: 10.1007/s00259-018-3965-8
          DOI: 10.1007/s00259-018-3965-8
          PubMed ID: 29497802
          SO-VID: aa03ef2b-0127-4ff0-85da-df264f12dad1
          History

          Keywords: 68Ga-PSMA-11,Mediastinal,Mediastinal/paraaortal,PET/CT,PSMA,Prostate cancer,Prostate-specific membrane antigen,Lymph nodes
          Data availability:
          Keywords: 68Ga-PSMA-11, Mediastinal, Mediastinal/paraaortal, PET/CT, PSMA, Prostate cancer, Prostate-specific membrane antigen, Lymph nodes

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