18
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Strategies for silencing human disease using RNA interference.

      Nature reviews. Genetics

      Animals, Eye Diseases, genetics, therapy, Genetic Therapy, methods, trends, Humans, Neoplasms, Neurodegenerative Diseases, RNA Interference, RNA, Small Interfering, Virus Diseases

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Since the first description of RNA interference (RNAi) in animals less than a decade ago, there has been rapid progress towards its use as a therapeutic modality against human diseases. Advances in our understanding of the mechanisms of RNAi and studies of RNAi in vivo indicate that RNAi-based therapies might soon provide a powerful new arsenal against pathogens and diseases for which treatment options are currently limited. Recent findings have highlighted both promise and challenges in using RNAi for therapeutic applications. Design and delivery strategies for RNAi effector molecules must be carefully considered to address safety concerns and to ensure effective, successful treatment of human diseases.

          Related collections

          Author and article information

          Journal
          17304245
          10.1038/nrg2006

          Comments

          Comment on this article