This article discusses the essence and the present state of migration in Ukraine. It investigates the migration trends in Ukraine and analyzes the destinations and age groups of Ukrainian labor migrants. The imperfection of a domestic statistical base and consequence of increased scales of international labor migration is parsed. The main socio-economic causes of labor migration and their consequences for the economy of Ukraine are revealed. The article also analyzes the main outcomes of migration of one of the family members for marital relations and relations between parents and children, considers the problems of social orphanhood or the so-called "euro orphanhood " as well as problems of care for the elderly as a consequence of the departure of children abroad. The economic substantiation of the influence of the outflow of labor resources on the sphere of social security, the state and peculiarities of functioning of Ukrainian Medical Institutions is provided.