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      In‐hospital management of persons with haemophilia and COVID‐19: practical guidance

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          Abstract

          A new disease (COVID‐19) caused by a coronavirus (SARS‐CoV‐2) that appeared in China at the end of 2019 is currently spreading globally. This emerging virus is mainly responsible for respiratory tract infections and potentially fatal pneumonia, mainly in more frail patients. Persons with haemophilia of variable severity and from all parts of the world will likely be infected and develop COVID‐19.

          We here propose practical guidance for the in‐hospital specific management of haemophilia persons with COVID‐19 including their possible transfer to intensive care unit. Rapid identification of the haemophilia status, undelayed and regular liaison with the haemophilia team, proper therapy with factor concentrates or alternative treatments appear instrumental to prevent haemophilia‐related complications in this setting.

          Information of patients and their families about COVID‐19, psychological support and good appreciation of the impact of haemophilia on therapeutic decisions including end of life directives are also addressed.

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          Author and article information

          Contributors
          cedric.hermans@uclouvain.be
          Journal
          Haemophilia
          Haemophilia
          10.1111/(ISSN)1365-2516
          HAE
          Haemophilia
          John Wiley and Sons Inc. (Hoboken )
          1351-8216
          1365-2516
          08 May 2020
          : 10.1111/hae.14045
          Affiliations
          [ 1 ] Haemostasis and Thrombosis Unit Division of Haematology Cliniques universitaires Saint‐Luc Université catholique de Louvain Brussels Belgium
          [ 2 ] Division of Intensive Care Cliniques universitaires Saint‐Luc Université catholique de Louvain Brussels Belgium
          [ 3 ] Division of Infectious Diseases Department of Internal Medicine Cliniques universitaires Saint‐Luc Université catholique de Louvain Brussels Belgium
          Author notes
          [*] [* ] Correspondence

          Cedric Hermans, MD, PhD, FRCP (Lon, Edin), Haemostasis and Thrombosis Unit, Division of Adult Haematology, St‐Luc University Hospital, Université catholique de Louvain (UCLouvain), Avenue Hippocrate 10 ‐ 1200 Brussels, BELGIUM

          Email: cedric.hermans@ 123456uclouvain.be

          Author information
          https://orcid.org/0000-0001-5429-8437
          https://orcid.org/0000-0003-2222-0357
          Article
          HAE14045
          10.1111/hae.14045
          7272941
          32384183
          aa5ae71a-ad14-49a6-90c4-4c0d54a3c09a
          This article is protected by copyright. All rights reserved.

          This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

          History
          Page count
          Figures: 0, Tables: 0, Pages: 14, Words: 227
          Categories
          Original Article
          Original Articles
          Custom metadata
          2.0
          accepted-manuscript
          Converter:WILEY_ML3GV2_TO_JATSPMC version:5.8.3 mode:remove_FC converted:05.06.2020

          Hematology
          covid‐19,guidance,haemophilia,sars‐cov2
          Hematology
          covid‐19, guidance, haemophilia, sars‐cov2

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