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      Influence of Left Ventricular Diastole on Left Atrial Appendage Blood Flow in Patients with Nonrheumatic Atrial Fibrillation

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          Abstract

          The function of the left atrial appendage (LAA) reflected by the Doppler flow velocity at the outlet of the left atrial appendage has been reported to be correlated with spontaneous echo contrast and thrombus formation. To evaluate the influence of left ventricular diastole on LAA flow during atrial fibrillation (AF), 81 patients with chronic nonrheumatic AF were studied by transesophageal echocardiography. The peak outflow velocity of LAA during ventricular diastole was higher than that during ventricular systole (0.23 ± 0.14 vs. 0.15 ± 0.13 m/s, p < 0.001). The peak inflow velocity of LAA during ventricular diastole was also higher than that during ventricular systole (0.22 ± 0.15 vs. 0.18 ± 0.11 m/s, p < 0.01). Patients with a good left ventricular ejection fraction have a significantly higher peak LAA outflow velocity and a larger diastolic augmentation of LAA outflow (defined by the difference of LAA outflow between systolic and diastolic phases) than patients with an impaired left ventricular function. Thus, left ventricular diastole might have an influence on LAA flow during AF. In addition, the left ventricular function might be considered a predictor of subsequent thromboembolism from the viewpoint of its effect on LAA flow in patients with nonrheumatic AF.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1997
          1997
          21 November 2008
          : 88
          : 6
          : 563-568
          Affiliations
          Departments of Internal Medicine, aCheng-Ching Hospital, Taichung, and bNational Taiwan University Hospital, Taipei, Taiwan
          Article
          177420 Cardiology 1997;88:563–568
          10.1159/000177420
          9397313
          © 1997 S. Karger AG, Basel

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          Page count
          Pages: 6
          Categories
          Noninvasive and Diagnostic Cardiology

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