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      Josep Trueta (1897–1977): Military Surgeon and Pioneer Investigator of Acute Renal Failure

      American Journal of Nephrology

      S. Karger AG

      J. Trueta, Posttraumatic acute renal failure, Military medicine

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          Abstract

          The great Spanish military and orthopedic surgeon J. Trueta gained his field and clinical experience in the Spanish civil war (1936–1939) and in Britain during World War II. As part of his major contribution to traumatology, he searched for the causes of the characteristic oliguria of combat casualties. For this purpose he studied the effect of induced ischemic myopathy on renal perfusion in the rabbit. He and his coworkers demonstrated conclusively that in this model there was an extreme renal cortical vasoconstriction with preservation of the medullary circulation. This early first demonstration of posttraumatic vasomotor nephropathy was independently confirmed 20 years later in the USA when ‘preferential renal cortical ischemia’ was demonstrated in acute renal failure in man. Thus, Trueta discovered in the early 40s the circulatory component of acute renal failure as part of his monumental contribution to military medicine.

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          Hypoxia of the renal medulla--its implications for disease.

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            Author and article information

            Journal
            AJN
            Am J Nephrol
            10.1159/issn.0250-8095
            American Journal of Nephrology
            S. Karger AG
            978-3-8055-6855-5
            978-3-318-00128-0
            0250-8095
            1421-9670
            1999
            April 1999
            23 April 1999
            : 19
            : 2
            : 343-345
            Affiliations
            Dr. Rebecca Chutick Crush Syndrome Center and Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
            Article
            13473 Am J Nephrol 1999;19:343–345
            10.1159/000013473
            10213840
            © 1999 S. Karger AG, Basel

            Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

            Page count
            References: 10, Pages: 3
            Product
            Self URI (application/pdf): https://www.karger.com/Article/Pdf/13473
            Categories
            Origins of Nephrology – The Modern Era

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