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      Josep Trueta (1897–1977): Military Surgeon and Pioneer Investigator of Acute Renal Failure

      American Journal of Nephrology

      S. Karger AG

      J. Trueta, Posttraumatic acute renal failure, Military medicine

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          The great Spanish military and orthopedic surgeon J. Trueta gained his field and clinical experience in the Spanish civil war (1936–1939) and in Britain during World War II. As part of his major contribution to traumatology, he searched for the causes of the characteristic oliguria of combat casualties. For this purpose he studied the effect of induced ischemic myopathy on renal perfusion in the rabbit. He and his coworkers demonstrated conclusively that in this model there was an extreme renal cortical vasoconstriction with preservation of the medullary circulation. This early first demonstration of posttraumatic vasomotor nephropathy was independently confirmed 20 years later in the USA when ‘preferential renal cortical ischemia’ was demonstrated in acute renal failure in man. Thus, Trueta discovered in the early 40s the circulatory component of acute renal failure as part of his monumental contribution to military medicine.

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          Hypoxia of the renal medulla--its implications for disease.


            Author and article information

            Am J Nephrol
            American Journal of Nephrology
            S. Karger AG
            April 1999
            23 April 1999
            : 19
            : 2
            : 343-345
            Dr. Rebecca Chutick Crush Syndrome Center and Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
            13473 Am J Nephrol 1999;19:343–345
            © 1999 S. Karger AG, Basel

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            Page count
            References: 10, Pages: 3
            Self URI (application/pdf): https://www.karger.com/Article/Pdf/13473
            Origins of Nephrology – The Modern Era


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