2
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      An Anatomy of the Intergenerational Correlation of Educational Attainment -Learning from the Educational Attainments of Norwegian Twins and their Children

      , , , ,
      Research in Social Stratification and Mobility
      Elsevier BV

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Related collections

          Most cited references78

          • Record: found
          • Abstract: found
          • Article: not found

          Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

          Here we conducted a large-scale genetic association analysis of educational attainment in a sample of approximately 1.1 million individuals and identify 1,271 independent genome-wide-significant SNPs. For the SNPs taken together, we found evidence of heterogeneous effects across environments. The SNPs implicate genes involved in brain-development processes and neuron-to-neuron communication. In a separate analysis of the X chromosome, we identify 10 independent genome-wide-significant SNPs and estimate a SNP heritability of around 0.3% in both men and women, consistent with partial dosage compensation. A joint (multi-phenotype) analysis of educational attainment and three related cognitive phenotypes generates polygenic scores that explain 11-13% of the variance in educational attainment and 7-10% of the variance in cognitive performance. This prediction accuracy substantially increases the utility of polygenic scores as tools in research.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Meta-analysis of the heritability of human traits based on fifty years of twin studies.

            Despite a century of research on complex traits in humans, the relative importance and specific nature of the influences of genes and environment on human traits remain controversial. We report a meta-analysis of twin correlations and reported variance components for 17,804 traits from 2,748 publications including 14,558,903 partly dependent twin pairs, virtually all published twin studies of complex traits. Estimates of heritability cluster strongly within functional domains, and across all traits the reported heritability is 49%. For a majority (69%) of traits, the observed twin correlations are consistent with a simple and parsimonious model where twin resemblance is solely due to additive genetic variation. The data are inconsistent with substantial influences from shared environment or non-additive genetic variation. This study provides the most comprehensive analysis of the causes of individual differences in human traits thus far and will guide future gene-mapping efforts. All the results can be visualized using the MaTCH webtool.
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Genotype-environment interaction and correlation in the analysis of human behavior.

                Bookmark

                Author and article information

                Journal
                Research in Social Stratification and Mobility
                Research in Social Stratification and Mobility
                Elsevier BV
                02765624
                April 2022
                April 2022
                : 100691
                Article
                10.1016/j.rssm.2022.100691
                ac009d05-8dd3-4c91-9833-45a4cb0b8057
                © 2022

                https://www.elsevier.com/tdm/userlicense/1.0/

                http://creativecommons.org/licenses/by/4.0/

                History

                Comments

                Comment on this article