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      Sgarbossa Criteria are Highly Specific for Acute Myocardial Infarction with Pacemakers

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          Abstract

          Objective:

          In 1996 Sgarbossa reviewed 17 ventricular-paced electrocardiograms (ECGs) in acute myocardial infarction (AMI) for signs of ischemia. Several characteristics of the paced ECG were predictive of AMI. We sought to evaluate the criteria in ventricular-paced ECGs in an emergency department (ED) cohort.

          Methods:

          Ventricular-paced ECGs in patients with elevated cardiac markers within 12 hours of the ED ECG and a diagnosis of AMI were identified retrospectively (n=57) and compared with a control group of patients with ventricular-paced ECGs and negative cardiac markers (n=99). A blinded board certified cardiologist reviewed all ECGs for Sgarbossa criteria. This study was approved by the institutional review board.

          Results:

          Application of Sgarbossa’s criteria to the paced ECGs revealed the following:

          1. The sensitivity of “ST-segment elevation of 1 mm concordant with the QRS complex” was unable to be calculated as no ECG fit this criterion;

          2. For “ST-segment depression of 1 mm in lead V1, V2, or V3,” the sensitivity was 19% (95% CI 11–31%), specificity 81% (95% CI 72–87%), with a likelihood ratio of 1.06 (0.63–1.64);

          3. For “ST-segment elevation >5mm discordant with the QRS complex,” the sensitivity was 10% (95% CI 5–21%), specificity 99% (95% CI 93–99%), with a likelihood ratio of 5.2 (1.3 – 21).

          Conclusion:

          In our review of ventricular-paced ECGs, the most clinically useful Sgarbossa criterion in identifying AMI was ST-segment elevation >5mm discordant with the QRS complex. This characteristic may prove helpful in identifying patients who may ultimately benefit from early aggressive AMI treatment strategies.

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          Most cited references11

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          Long-term outcome after primary angioplasty: report from the primary angioplasty in myocardial infarction (PAMI-I) trial.

          This study sought to compare the two-year outcome after primary percutaneous coronary angioplasty or thrombolytic therapy for acute myocardial infarction. Primary angioplasty, that is, angioplasty without antecedent thrombolytic therapy, has been shown to be an effective reperfusion modality for patients suffering an acute myocardial infarction. This report reviews the two-year clinical outcome of patients randomized in the Primary Angioplasty in Myocardial Infarction trial. At 12 clinical centers, 395 patients who presented within 12 h of the onset of myocardial infarction were randomized to undergo primary angioplasty (195 patients) or to receive tissue-type plasminogen activator (t-PA) (200 patients) followed by conservative care. Patients were followed by physician visits, phone call, letter and review of hospital records for any hospital admission at one month, six months, one year and two years. At two years, patients undergoing primary angioplasty had less recurrent ischemia (36.4% vs. 48% for t-PA, p = 0.026), lower reintervention rates (27.2% vs. 46.5% for t-PA, p < 0.0001) and reduced hospital readmission rates (58.5% vs. 69.0% for t-PA, p = 0.035). The combined end point of death or reinfarction was 14.9% for angioplasty versus 23% for t-PA, p = 0.034. Multivariate analysis found angioplasty to be independently predictive of a reduction in death, reinfarction or target vessel revascularization (p = 0.0001). The initial benefit of primary angioplasty performed by experienced operators is maintained over a two-year follow-up period with improved infarct-free survival and reduced rate of reintervention.
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            Clinical policy: critical issues in the evaluation and management of adult patients with non-ST-segment elevation acute coronary syndromes.

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              • Abstract: not found
              • Article: not found

              Early electrocardiographic diagnosis of acute myocardial infarction in the presence of ventricular paced rhythm. GUSTO-I investigators.

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                Author and article information

                Journal
                West J Emerg Med
                WestJEM
                Western Journal of Emergency Medicine
                Department of Emergency Medicine, University of California, Irvine School of Medicine
                1936-900X
                1936-9018
                September 2010
                : 11
                : 4
                : 354-357
                Affiliations
                [* ]Georgetown University, Department of Emergency Medicine, Washington, DC
                [] Georgetown University, Division of Cardiology, Department of Cardiology, Washington, DC
                Author notes
                Address for Correspondence: Kevin Maloy, MD, Department of Emergency Medicine, Georgetown University Hospital, 3700 Reservior Road NW, First Floor CCC Building, Washington, DC 20057. Email maloykr@ 123456georgetown.edu

                Supervising Section Editor: Matthew Strehlow, MD

                Article
                wjem11_4p354
                2967688
                21079708
                ac076a95-80c1-4aca-9a92-140672fa359f
                Copyright © 2010 the authors.

                This is an Open Access article distributed under the terms of the Creative Commons Non-Commercial Attribution License, which permits its use in any digital medium, provided the original work is properly cited and not altered. For details, please refer to http://creativecommons.org/licenses/by-nc-nd/3.0/. Authors grant Western Journal of Emergency Medicine a nonexclusive license to publish the manuscript.

                History
                : 20 February 2009
                : 29 July 2009
                : 16 November 2009
                Categories
                Cardiology
                Original Research

                Emergency medicine & Trauma
                Emergency medicine & Trauma

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