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      Long-term storable and shippable lipid bilayer membrane platform.

      Lab on a Chip
      Freezing, Lipid Bilayers

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          Abstract

          The fragility and short lifetimes characteristic of conventionally formed lipid bilayer membranes has necessitated their preparation to be at the time and point of use. By using high freezing-point lipid-solvent mixtures, the process of lipid bilayer self-assembly may be reversibly arrested. In solid form, the bilayer precursor can be stored indefinitely and is sufficiently robust to withstand commercial shipping. Upon thawing, bilayer self-assembly resumes, resulting in a biologically functional membrane. Combination of this membrane precursor with an inexpensive chip results in a compact, practical, and disposable platform for ion channel measurements.

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          Author and article information

          Journal
          18813400
          10.1039/b807932c

          Freezing,Lipid Bilayers
          Freezing, Lipid Bilayers

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