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      Effect of uncontrolled fertilization and heavy metal toxicity associated with arsenic(As), lead(Pb) and cadmium (Cd), and possible remediation

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      Toxicology
      Elsevier BV

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          Abstract

          <p class="first" id="d5407054e83">In this growing age of population,agriculture plays a significant role by providing food and employment to millions of people. But to meet the growing need of food day by day the demand of fast and quality plant production becomes a must. Fertilization is one of such activities which are people accustomed to do for this purpose from a very long time. But the excessive uses of chemical fertilizers are showing negative influence on the environmental and public health. The paper mainly focuses on how the excessive use of chemical fertilizers are affecting the soil health as well as the water bodies by accumulating heavy metals (HMs) and other chemical elements present in them and the possible remediation measures.In adequate levels, all heavy metals are hazardous. However, some of them e.g., arsenic (As), lead (Pb) and Cadmium (Cd) are of particular relevance due to their environmental concentrations. The paper also provides a comprehensive discussion of the sources, uses, toxicity, and remediation of these particular HMs. </p>

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          Most cited references114

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          Heavy metal toxicity and the environment.

          Heavy metals are naturally occurring elements that have a high atomic weight and a density at least five times greater than that of water. Their multiple industrial, domestic, agricultural, medical, and technological applications have led to their wide distribution in the environment, raising concerns over their potential effects on human health and the environment. Their toxicity depends on several factors including the dose, route of exposure, and chemical species, as well as the age, gender, genetics, and nutritional status of exposed individuals. Because of their high degree of toxicity, arsenic, cadmium, chromium, lead, and mercury rank among the priority metals that are of public health significance. These metallic elements are considered systemic toxicants that are known to induce multiple organ damage, even at lower levels of exposure. They are also classified as human carcinogens (known or probable) according to the US Environmental Protection Agency and the International Agency for Research on Cancer. This review provides an analysis of their environmental occurrence, production and use, potential for human exposure, and molecular mechanisms of toxicity, genotoxicity, and carcinogenicity.
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            Heavy metals, occurrence and toxicity for plants: a review

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              Soil contamination in China: current status and mitigation strategies.

              China faces great challenges in protecting its soil from contamination caused by rapid industrialization and urbanization over the last three decades. Recent nationwide surveys show that 16% of the soil samples, 19% for the agricultural soils, are contaminated based on China’s soil environmental quality limits, mainly with heavy metals and metalloids. Comparisons with other regions of the world show that the current status of soil contamination, based on the total contaminant concentrations, is not worse in China. However, the concentrations of some heavy metals in Chinese soils appear to be increasing at much greater rates. Exceedance of the contaminant limits in food crops is widespread in some areas, especially southern China, due to elevated inputs of contaminants, acidic nature of the soil and crop species or cultivars prone to heavy metal accumulation. Minimizing the transfer of contaminants from soil to the food chain is a top priority. A number of options are proposed, including identification of the sources of contaminants to agricultural systems, minimization of contaminant inputs, reduction of heavy metal phytoavailability in soil with liming or other immobilizing materials, selection and breeding of low accumulating crop cultivars, adoption of appropriate water and fertilizer management, bioremediation, and change of land use to grow nonfood crops. Implementation of these strategies requires not only technological advances, but also social-economic evaluation and effective enforcement of environmental protection law.
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                Author and article information

                Journal
                Toxicology
                Toxicology
                Elsevier BV
                0300483X
                July 2022
                July 2022
                : 477
                : 153274
                Article
                10.1016/j.tox.2022.153274
                35905945
                ac31aa32-acdb-4d9a-8507-af4a38f86e05
                © 2022

                https://www.elsevier.com/tdm/userlicense/1.0/

                https://doi.org/10.15223/policy-017

                https://doi.org/10.15223/policy-037

                https://doi.org/10.15223/policy-012

                https://doi.org/10.15223/policy-029

                https://doi.org/10.15223/policy-004

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