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      Nomenclature of monocytes and dendritic cells in blood.

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          Abstract

          Monocytes and cells of the dendritic cell lineage circulate in blood and eventually migrate into tissue where they further mature and serve various functions, most notably in immune defense. Over recent years these cells have been characterized in detail with the use of cell surface markers and flow cytometry, and subpopulations have been described. The present document proposes a nomenclature for these cells and defines 3 types of monocytes (classical, intermediate, and nonclassical monocytes) and 3 types of dendritic cells (plasmacytoid and 2 types of myeloid dendritic cells) in human and in mouse blood. This classification has been approved by the Nomenclature Committee of the International Union of Immunological Societies, and we are convinced that it will facilitate communication among experts and in the wider scientific community.

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          Author and article information

          Journal
          Blood
          Blood
          American Society of Hematology
          1528-0020
          0006-4971
          Oct 21 2010
          : 116
          : 16
          Affiliations
          [1 ] Helmholtz Zentrum München, Gauting, Germany. ziegler-heitbrock@helmholtz-muenchen.de
          Article
          S0006-4971(20)31241-6
          10.1182/blood-2010-02-258558
          20628149
          ac31afff-1d27-4462-9889-9fef5ce1c260
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