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      The tumor immune microenvironment in pancreatic cancer and its potential in the identification of immunotherapy biomarkers.

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          Abstract

          Pancreatic cancer (PC) has an extremely poor prognosis, even with surgical resection and triplet chemotherapy treatment. Cancer immunotherapy has been recently approved for tumor-agnostic treatment with genome analysis, including in PC. However, it has limited efficacy.

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          Author and article information

          Journal
          Expert Rev Mol Diagn
          Expert review of molecular diagnostics
          Informa UK Limited
          1744-8352
          1473-7159
          2023
          : 23
          : 12
          Affiliations
          [1 ] Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan.
          [2 ] Division of Medical Oncology, Department of Medicine, Showa University School of Medicine, Shinagawa, Tokyo, Japan.
          [3 ] Department of Clinical Immuno-Oncology, Clinical Research Institute for Clinical Pharmacology and Therapeutics, Showa University, Setagaya, Tokyo, Japan.
          Article
          10.1080/14737159.2023.2281482
          37947389
          ac537cf0-bcab-45cd-a1c3-e2867f3ef8db
          History

          immunotherapy,microbiome,pancreatic cancer,Cancer-associated fibroblast,exosome

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