Blog
About

2
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Characteristics and related factors of low-risk infection among HPV-positive women in Shenzhen, 2014-2016

      Read this article at

      ScienceOpenPublisher
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Objective To explore the characteristics and related factors of low-risk human papilloma virus (HPV) infection among HPV-positive women in Shenzhen.

          Methods Women who participated in HPV testing for cervical cancer screening and then detected HPV positive between 2014 and 2016 were observed. Chi-square tests were used for analyzing low-risk HPV distribution among different subgroups of women. An unconditional logistic regression model was applied to explore the related factors of low-risk HPV infection.

          Results Totally 10 624 HPV-positive women were included in the analysis, in which 1 077 women were detected with low-risk HPV infection (10.1%). The proportions of different low-risk HPV genotypes were HPV 43 (3.3%), HPV 6 (2.6%), HPV 42 (2.3%), HPV 11 (2.0%), HPV 44 (0.4%), and HPV 81 (0.1%), from high to low. Except for nationality, the distributions of low-risk HPV infection varied significantly when stratified by age, occupation, marital status, screening types and years, and high-risk HPV 16/18 infected status ( P<0.05). Multivariate logistic regression analysis showed that compared with women younger than 25 years old, women in other age groups had decreased risks of low-risk HPV infection; single/divorced/widowed women had a increased risk of low-risk HPV infection than women who got married [ OR (95% CI): 1.91 (1.47-2.47)]; women infected by HPV 16 /18 had a decreased risk of low-risk HPV infection than uninfected individuals [ OR (95% CI): 0.25 (0.20-0.31)].

          Conclusion From 2014 to 2016, HPV 43 was the most common low-risk HPV genotype for women infected by HPV in Shenzhen area. Age, marital status, and high-risk HPV 16/18 infected status were associated factors for low-risk HPV infection.

          Abstract

          摘要: 目的 了解深圳市女性人乳头瘤病毒 (human papilloma virus, HPV) 阳性者低危型感染型别分布特征。 方法 以深圳地区2014—2016年参与子宫颈癌筛查的女性为研究对象, 分析HPV检测阳性且HPV基因分型检测为低 危型的HPV感染型别分布, 采用 χ 2检验进行组间比较, 并利用非条件logistic回归模型探讨低危型HPV感染的相关因 素。 结果共10 624例HPV阳性者纳入型别分析, 感染低危型HPV者共1 077例, 占10.1%。不同低危型别感染按比 例高到低分别为HPV 43 (3.3%) 、HPV 6 (2.6%) 、HPV 42 (2.3%) 、HPV 11 (2.0%) 、HPV 44 (0.4%) 和HPV 81 (0.1%) 。除民 族外, 不同年龄、职业、婚姻状况、筛查形式、筛查年份及高危型HPV 16/18感染状态者低危型HPV感染比例分布差异有 统计学意义 ( P<0.05) 。多因素Logistic回归分析结果显示, 以25岁及以下者为参照, 其他高年龄组发生低危型HPV感 染的风险降低; 以已婚者为参照, 未婚/离异/丧偶者发生低危型HPV感染的风险更高 ( OR 和95% CI:1.91, 1.47~ 2.47) ; 与无高危型HPV 16/18者相比, 感染高危型HPV 16/18者发生低危型HPV感染的风险降低 ( OR 和95% CI:0.25, 0.20~0.31) 。 结论2014—2016年深圳地区女性HPV阳性者低危型别感染以HPV 43最为常见, 年龄、婚姻状况、高危型 HPV 16/18感染可能是低危型HPV感染的相关因素。

          Related collections

          Author and article information

          Journal
          CTM
          China Tropical Medicine
          China Tropical Medicine (China )
          1009-9727
          01 November 2019
          01 January 2020
          : 19
          : 11
          : 1054-1057
          Affiliations
          1Department of Healthcare, Affiliated Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Shenzhen, Guangdong 518048, China
          Author notes
          *Corresponding author: WANG Yueyun, E-mail: wangyueyun@ 123456126.com
          Article
          j.cnki.46-1064/r.2019.11.11
          10.13604/j.cnki.46-1064/r.2019.11.11
          © 2019 Editorial Department of China Tropical Medicine

          This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc/4.0/.

          Product
          Self URI (journal page): http://www.cntropmed.com
          Categories
          Journal Article

          Comments

          Comment on this article