Lead analysts: François Aguet
1
*, Andrew A. Brown
2,
3,
4
*, Stephane E. Castel
5,
6
*, Joe R. Davis
7,
8
*, Yuan He
9
*, Brian Jo
10
*, Pejman Mohammadi
5,
6
*, YoSon Park
11
*, Princy Parsana
12
*, Ayellet V. Segrè
1
*, Benjamin J. Strober
9
*, Zachary Zappala
7,
8
*
Laboratory, Data Analysis & Coordinating Center (LDACC): Beryl B. Cummings
1,
13
, Ellen T. Gelfand
1
, Kane Hadley
1
, Katherine H. Huang
1
, Monkol Lek
1,
13
, Xiao Li
1
, Jared L. Nedzel
1
, Duyen Y. Nguyen
1
, Michael S. Noble
1
, Timothy J. Sullivan
1
, Taru Tukiainen
1,
13
, Daniel G. MacArthur
1,
13
, Gad Getz
1,
14
NIH program management: Anjene Addington
15
, Ping Guan
16
, Susan Koester
15
, A. Roger Little
17
, Nicole C. Lockhart
18
, Helen M. Moore
16
, Abhi Rao
16
, Jeffery P. Struewing
19
, Simona Volpi
19
Biospecimen collection: Lori E. Brigham
20
, Richard Hasz
21
, Marcus Hunter
22
, Christopher Johns
23
, Mark Johnson
24
, Gene Kopen
25
, William F. Leinweber
25
, John T. Lonsdale
25
, Alisa McDonald
25
, Bernadette Mestichelli
25
, Kevin Myer
22
, Bryan Roe
22
, Michael Salvatore
25
, Saboor Shad
25
, Jeffrey A. Thomas
25
, Gary Walters
24
, Michael Washington
24
, Joseph Wheeler
23
, Jason Bridge
26
, Barbara A. Foster
27
, Bryan M. Gillard
27
, Ellen Karasik
27
, Rachna Kumar
27
, Mark Miklos
26
, Michael T. Moser
27
, Scott D. Jewell
28
, Robert G. Montroy
28
, Daniel C. Rohrer
28
, Dana Valley
28
, Deborah C. Mash
29
, David A. Davis
29
Pathology: Leslie Sobin
30
, Mary E. Barcus
30
, Philip A. Branton
16
eQTL manuscript working group: Nathan S. Abell
7,
8
, Brunilda Balliu
8
, Olivier Delaneau
2,
3,
4
, Laure Frésard
8
, Eric R. Gamazon
31
, Diego Garrido-Martín
32,
33
, Ariel D. H. Gewirtz
10
, Genna Gliner
34
, Michael J. Gloudemans
8,
35
, Buhm Han
36
, Amy Z. He
12
, Farhad Hormozdiari
37
, Xin Li
8
, Boxiang Liu
8,
38
, Eun Yong Kang
39
, Ian C. McDowell
40
, Halit Ongen
2,
3,
4
, John J. Palowitch
41
, Christine B. Peterson
42
, Gerald Quon
1,
43
, Stephan Ripke
13,
44
, Ashis Saha
12
, Andrey A. Shabalin
45
, Tyler C. Shimko
7,
8
, Jae Hoon Sul
46
, Nicole A. Teran
7,
8
, Emily K. Tsang
8,
35
, Hailei Zhang
1
, Yi-Hui Zhou
47
, Carlos D. Bustamante
7,
48
, Nancy J. Cox
31
, Roderic Guigó
32,
33
, Manolis Kellis
1,
43
, Mark I. McCarthy
49,
50,
51
, Donald F. Conrad
52,
53
, Eleazar Eskin
37,
39
, Gen Li
54
, Andrew B. Nobel
41
, Chiara Sabatti
48,
55
, Barbara E. Stranger
56
, Xiaoquan Wen
57
, Fred A. Wright
58
, Kristin G. Ardlie
1
, Emmanouil T. Dermitzakis
2,
3,
4
, Tuuli Lappalainen
5,
6
Corresponding authors: Alexis Battle
12
§
, Christopher D. Brown
11
§
, Barbara E. Engelhardt
59
§
& Stephen B. Montgomery
7,
8
§
[1]
The Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
[2]
Department of Genetic Medicine and Development, University of Geneva Medical School,
1211 Geneva, Switzerland.
[3]
Institute for Genetics and Genomics in Geneva (iG3), University of Geneva, 1211 Geneva,
Switzerland.
[4]
Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland.
[5]
New York Genome Center, New York, New York 10013, USA.
[6]
Department of Systems Biology, Columbia University, New York, New York 10032, USA.
[7]
Department of Genetics, Stanford University, Stanford, California 94305, USA.
[8]
Department of Pathology, Stanford University, Stanford, California 94305, USA.
[9]
Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland
21218, USA.
[10]
Lewis Sigler Institute, Princeton University, Princeton, New Jersey 08450, USA.
[11]
Department of Genetics and Institute for Biomedical Informatics, Perelman School of
Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
[12]
Department of Computer Science, Johns Hopkins University, Baltimore, Maryland 21218,
USA.
[13]
Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston,
Massachusetts 02114, USA.
[14]
Massachusetts General Hospital Cancer Center and Department of Pathology, Massachusetts
General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.
[15]
Division of Neuroscience and Basic Behavioral Science, National Institute of Mental
Health, Bethesda, Maryland 20892, USA.
[16]
Biorepositories and Biospecimen Research Branch, Cancer Diagnosis Program, National
Cancer Institute, Bethesda, Maryland 20892, USA.
[17]
Division of Neuroscience and Behavior, National Institute on Drug Abuse, Bethesda,
Maryland 20892, USA.
[18]
Division of Genomics and Society, National Human Genome Research Institute, Bethesda,
Maryland 20892, USA.
[19]
Division of Genomic Medicine, National Human Genome Research Institute, Bethesda,
Maryland 20892, USA.
[20]
Washington Regional Transplant Community, Annandale, Virginia 22003, USA.
[21]
Gift of Life Donor Program, Philadelphia, Pennsylvania 19103, USA.
[22]
LifeGift, Houston, Texas 77055, USA.
[23]
Center for Organ Recovery and Education, Pittsburgh, Pennsylvania 15238, USA.
[24]
LifeNet Health, Virginia Beach, Virginia 23453, USA.
[25]
National Disease Research Interchange, Philadelphia, Pennsylvania 19103, USA.
[26]
Unyts, Buffalo, New York 14203, USA.
[27]
Pharmacology and Therapeutics, Roswell Park Cancer Institute, Buffalo, New York 14263,
USA.
[28]
Van Andel Research Institute, Grand Rapids, Michegan 49503, USA.
[29]
Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida
33136, USA.
[30]
Leidos Biomedical Research Inc., Rockville, Maryland 20852, USA.
[31]
Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville,
Tennessee 37232, USA.
[32]
Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology,
88, 08003 Barcelona, Spain.
[33]
Universitat Pompeu Fabra (UPF), 08002 Barcelona, Spain.
[34]
Department of Operations Research and Financial Engineering, Princeton University,
Princeton, New Jersey 84540, USA.
[35]
Biomedical Informatics Program, Stanford University, Stanford, California 94305, USA.
[36]
Department of Convergence Medicine, University of Ulsan College of Medicine, Asan
Medical Center, Seoul, 05505, Korea.
[37]
Department of Human Genetics, University of California, Los Angeles, California 90095,
USA.
[38]
Department of Biology, Stanford University, Stanford, California 94305, USA.
[39]
Department of Computer Science, University of California, Los Angeles, California
90095, USA.
[40]
Computational Biology and Bioinformatics Graduate Program, Duke University, Durham,
North Carolina 27708, USA.
[41]
Department of Statistics and Operations Research, University of North Carolina, Chapel
Hill, North Carolina 27599, USA.
[42]
Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston,
Texas 77030, USA.
[43]
Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, Massachusetts
02139, USA.
[44]
Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge,
Massachusetts 02142, USA.
[45]
Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University,
Richmond, Virginia 23298, USA.
[46]
Department of Psychiatry and Biobehavioral Sciences, University of California, Los
Angeles, California 90095, USA.
[47]
Bioinformatics Research Center and Department of Biological Sciences, North Carolina
State University, Raleigh, North Carolina 27695, USA.
[48]
Department of Biomedical Data Science, Stanford University, Stanford, California 94305,
USA.
[49]
Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University
of Oxford, Oxford OX3 7BN, UK.
[50]
Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of
Medicine, University of Oxford, Oxford OX3 9DU, UK.
[51]
Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford
OX3 7LE, UK.
[52]
Department of Pathology & Immunology, Washington University School of Medicine, St.
Louis, Missouri 63110, USA.
[53]
Department of Genetics, Washington University School of Medicine, St. Louis, Missouri
63110, USA.
[54]
Department of Biostatistics, Mailman School of Public Health, Columbia University,
New York, New York 10032, USA.
[55]
Department of Statistics, Stanford University, Stanford, California 94305, USA.
[56]
Section of Genetic Medicine, Department of Medicine, Institute for Genomics and Systems
Biology, Center for Data Intensive Science, University of Chicago, Chicago, Illinois
60637, USA.
[57]
Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.
[58]
Bioinformatics Research Center, Departments of Statistics and Biological Sciences,
North Carolina State University, Raleigh, North Carolina 27695, USA.
[59]
Department of Computer Science and Center for Statistics and Machine Learning, Princeton
University, Princeton, New Jersey 08540, USA.
[*]
These authors contributed equally to this work.
[§]
These authors jointly supervised this work.