- Record: found
- Abstract: found
- Article: not found
Clinical significance of global two-dimensional strain as a surrogate parameter of myocardial fibrosis and cardiac events in patients with hypertrophic cardiomyopathy.
Makoto Saito
1 ,
Hideki Okayama ,
Toyofumi Yoshii ,
Haruhiko Higashi ,
Hiroe Morioka ,
Go Hiasa ,
Takumi Sumimoto ,
Shinji Inaba ,
Kazuhisa Nishimura ,
Katsuji Inoue ,
Akiyoshi Ogimoto ,
Yuji Shigematsu ,
Mareomi Hamada ,
Jitsuo Higaki
Jul 2012
Read this article at
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
Late gadolinium enhancement (LGE) on contrast-enhanced magnetic resonance imaging (MRI) in hypertrophic cardiomyopathy (HCM) has been reported to be associated with myocardial fibrosis and cardiac events. In patients with HCM, two-dimensional (2D) strain can identify subclinical global systolic dysfunction despite normal left ventricular (LV) chamber function. Therefore, this study tested the hypothesis that global 2D strain could detect subtle myocardial fibrosis and serve as a novel prognostic parameter in HCM patients.