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      Morbidity and Mortality of Notifiable Infectious Diseases in 2015 in China

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          Abstract

          Objective

          To determine morbidity and mortality from notifiable infectious diseases in China in 2015.

          Methods

          Descriptive analysis was used to analyze morbidity and mortality from notifiable diseases in China in 2015.

          Results

          In 2015, the morbidity rate for national notifiable diseases was 470.35 per 100,000 population, a decrease of 7.11% compared with the average for 2012–2014. The mortality rate was 1.23 per 100,000 population, a decrease of 1.27% compared with the average for 2012–2014. The percentage of laboratory diagnoses was 38.22%, an increase of 5.32% compared with 2012–2014. The five diseases with the highest reported incidences were hand, foot, and mouth disease, other infectious diarrhea, hepatitis B, tuberculosis, and syphilis. The diseases with the highest mortality reported were AIDS, tuberculosis, and rabies. Diseases transmitted by direct contact/fecal–oral transmission accounted for the largest proportion, 49.89%, of all reported cases, followed by blood-borne/sexually transmitted diseases, respiratory transmitted diseases, and zoonotic/vector-borne diseases. Pathogenic descriptive analysis showed that viral infectious diseases accounted for 68.48% of all cases, followed by bacterial infectious diseases and zoonotic/vector-borne diseases.

          Conclusion

          Epidemics of tuberculosis, dengue fever, brucellosis, AIDS, and rabies remain public health concerns in China. In addition, the proportion of laboratory-confirmed diagnoses of notifiable disease cases was low in 2015.

          Most cited references12

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          The changing epidemiology of dengue in China, 1990-2014: a descriptive analysis of 25 years of nationwide surveillance data

          Background Dengue has been a notifiable disease in China since 1 September 1989. Cases have been reported each year during the past 25 years of dramatic socio-economic changes in China, and reached a historical high in 2014. This study describes the changing epidemiology of dengue in China during this period, to identify high-risk areas and seasons and to inform dengue prevention and control activities. Methods We describe the incidence and distribution of dengue in mainland China using notifiable surveillance data from 1990-2014, which includes classification of imported and indigenous cases from 2005-2014. Results From 1990-2014, 69,321 cases of dengue including 11 deaths were reported in mainland China, equating to 2.2 cases per one million residents. The highest number was recorded in 2014 (47,056 cases). The number of provinces affected has increased, from a median of three provinces per year (range: 1 to 5 provinces) during 1990-2000 to a median of 14.5 provinces per year (range: 5 to 26 provinces) during 2001-2014. During 2005-2014, imported cases were reported almost every month and 28 provinces (90.3%) were affected. However, 99.8% of indigenous cases occurred between July and November. The regions reporting indigenous cases have expanded from the coastal provinces of southern China and provinces adjacent to Southeast Asia to the central part of China. Dengue virus serotypes 1, 2, 3, and 4 were all detected from 2009-2014. Conclusions In China, the area affected by dengue has expanded since 2000 and the incidence has increased steadily since 2012, for both imported and indigenous dengue. Surveillance and control strategies should be adjusted to account for these changes, and further research should explore the drivers of these trends. Please see related article: http://dx.doi.org/10.1186/s12916-015-0345-0 Electronic supplementary material The online version of this article (doi:10.1186/s12916-015-0336-1) contains supplementary material, which is available to authorized users.
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            Effectiveness of HBV Vaccination in Infants and Prediction of HBV Prevalence Trend under New Vaccination Plan: Findings of a Large-Scale Investigation

            Background Hepatitis B virus (HBV) infection remains a severe public health problem. Investigating its prevalence and trends is essential to prevention. Methods To evaluate the effectiveness of HBV vaccination under the 1992 Intervention Program for infants and predicted HBV prevalence trends under the 2011 Program for all ages. We conducted a community-based investigation of 761,544 residents of 12 counties in Zhejiang Province selected according to their location, population density, and economic development. The HBV prevalence trends were predicted by a time-shifting approach. HBV surface antigen (HBsAg) and alanine amino transferase (ALT) were determined. Results Of the 761,544 persons screened for HBsAg, 54,132 were positive (adjusted carrier rate 6.13%); 9,455 had both elevated ALT and a positive HBsAg test (standardized rate 1.18%). The standardized HBsAg carrier rate for persons aged ≤20 years was 1.51%. Key factors influencing HBV infection were sex, age, family history, drinking, smoking, employment as a migrant worker, and occupation. With the vaccination program implemented in 2011, we predict that by 2020, the HBsAg carrier rate will be 5.27% and that for individuals aged ≤34 years will reach the 2% upper limit of low prevalence according to the WHO criteria, with a standardized rate of 1.86%. Conclusions The national HBV vaccination program for infants implemented in 1992 has greatly reduced the prevalence of HBV infection. The 2011 program is likely to reduce HBV infection in Zhejiang Province to a low moderate prevalence, and perinatal transmission is expected to be controlled by 2020.
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              Analysis for the Global and China TB Epidemic Situation in 2015

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                Author and article information

                Contributors
                Journal
                Infectious Diseases and Translational Medicine
                Infect. Dis. Transl. Med.
                Infect. Dis. Transl. Med.
                International Biological and Medical Journals Publishing House Co., Limited (Room E16, 3/f, Yongda Commercial Building, No.97, Bonham Stand (Sheung Wan), HongKong )
                2411-2917
                20 November 2016
                20 November 2016
                : 2
                : 3
                : 80-85
                Affiliations
                From Division of Infectious diseases, Chinese Center for Disease Control and Prevention
                From Division of Infectious diseases, Chinese Center for Disease Control and Prevention
                From Division of Infectious diseases, Chinese Center for Disease Control and Prevention
                Center for Disease Control and Prevention of Hubei Province, China
                Center for Disease Control and Prevention of Qinghai Province, China
                From Division of Infectious diseases, Chinese Center for Disease Control and Prevention
                From Division of Infectious diseases, Chinese Center for Disease Control and Prevention
                From Division of Infectious diseases, Chinese Center for Disease Control and Prevention
                Author notes
                Correspondence to: Liping Wang, Email: wanglp@ 123456chinacdc.cn .

                †: These authors contributed equally to this work.

                Article
                10.11979/idtm.201603001
                acc0b8a5-3701-4671-be41-0caa3dfdd488

                This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

                History
                : 20 October 2016
                : 30 October 2016
                :
                Page count
                Figures: 1, Tables: 2, References: 18, Pages: 6
                Categories
                Original Research

                Medicine,Infectious disease & Microbiology
                Surveillance,Notifiable diseases,China,Descriptive analysis

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