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      Modelling and analysis of gene regulatory networks.

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          Abstract

          Gene regulatory networks have an important role in every process of life, including cell differentiation, metabolism, the cell cycle and signal transduction. By understanding the dynamics of these networks we can shed light on the mechanisms of diseases that occur when these cellular processes are dysregulated. Accurate prediction of the behaviour of regulatory networks will also speed up biotechnological projects, as such predictions are quicker and cheaper than lab experiments. Computational methods, both for supporting the development of network models and for the analysis of their functionality, have already proved to be a valuable research tool.

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          Author and article information

          Journal
          Nat Rev Mol Cell Biol
          Nature reviews. Molecular cell biology
          Springer Science and Business Media LLC
          1471-0080
          1471-0072
          Oct 2008
          : 9
          : 10
          Affiliations
          [1 ] The Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv 69978, Israel.
          Article
          nrm2503
          10.1038/nrm2503
          18797474
          aceace4d-f012-4a35-9e26-c57b53c3f7ec
          History

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