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      PET en el diagnóstico de la patología de tiroides Translated title: PET in diagnosis of thyroid diseases

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          Abstract

          RESUMEN Introducción y objetivos: La PET/TC es una técnica cuyas indicaciones en Oncología se encuentran en expansión y el cáncer de tiroides es una de ellas. Material y métodos: Revisión narrativa. Resultados: En el presente artículo se revisan las indicaciones establecidas hasta la fecha. Conclusiones: Así como aquellos campos en los que son necesarias investigaciones adicionales que permitan establecer la utilidad de esta técnica en los distintos tipos de patología maligna tiroidea.

          Translated abstract

          ABSTRACT Introduction: Introduction and objective: PET/CT is a technique which oncological indications are now increasing, being thyroid cancer one of them. Material and methods: Narrative review. Results: The present study is a review of well-known indications. Conclusions: As well as those fields in which more studies are needed to establish the utility of this technique in every kind of malignant thyroid pathology.

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          Most cited references15

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          2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.

          Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Since the American Thyroid Association's (ATA's) guidelines for the management of these disorders were revised in 2009, significant scientific advances have occurred in the field. The aim of these guidelines is to inform clinicians, patients, researchers, and health policy makers on published evidence relating to the diagnosis and management of thyroid nodules and differentiated thyroid cancer.
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            Medullary Thyroid Carcinoma: An Update on Imaging

            Medullary thyroid carcinoma (MTC), arising from the parafollicular C cells of the thyroid, accounts for 1–2% of thyroid cancers. MTC is frequently aggressive and metastasizes to cervical and mediastinal lymph nodes, lungs, liver, and bones. Although a number of new imaging modalities for directing the management of oncologic patients evolved over the last two decades, the clinical application of these novel techniques is limited in MTC. In this article, we review the biology and molecular aspects of MTC as an important background for the use of current imaging modalities and approaches for this tumor. We discuss the modern and currently available imaging techniques—advanced magnetic resonance imaging (MRI)-based techniques such as whole-body MRI, dynamic contrast-enhanced (DCE) technique, diffusion-weighted imaging (DWI), positron emission tomography/computed tomography (PET/CT) with 18F-FDOPA and 18F-FDG, and integrated positron emission tomography/magnetic resonance (PET/MR) hybrid imaging—for primary as well as metastatic MTC tumor, including its metastatic spread to lymph nodes and the most common sites of distant metastases: lungs, liver, and bones.
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              Postoperative fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography: an important imaging modality in patients with aggressive histology of differentiated thyroid cancer.

              Aggressive histopathologic subtypes of differentiated thyroid cancer (DTC) are fluorodeoxyglucose (FDG)-avid tumors and are at high risk for persistent/recurrent disease. In these patients, fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) is performed in cases of suspicion of recurrence based on thyroglobulin (Tg) levels or thyroglobulin antibodies (TgAb). The goals of this study were to evaluate the sensitivity of systematic postoperative FDG-PET/CT and to identify risk factors for abnormal FDG-PET/CT.
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                Author and article information

                Journal
                orl
                Revista ORL
                Rev. ORL
                Ediciones Universidad de Salamanca (Salamanca, Salamanca, Spain )
                2444-7986
                September 2020
                : 11
                : 3
                : 297-304
                Affiliations
                [1] Salamanca orgnameHospital Universitario de Salamanca orgdiv1Servicio de Medicina Nuclear España
                Article
                S2444-79862020000300007 S2444-7986(20)01100300007
                10.14201/orl.21520
                ad0119f6-4563-44ee-9440-422e07513277

                This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

                History
                : 30 September 2019
                : 14 October 2019
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 15, Pages: 8
                Product

                SciELO Spain

                Categories
                Artículo de revisión

                Carcinoma Medular,Carcinoma anaplásico,FDG,PET/TC,FDOPA,Anaplastic Carcinoma,Medullary Carcinoma,Differentiated carcinoma,Thyroid,PET/CT,Carcinoma diferenciado,Tiroides

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