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      Comparing methods of measurement: why plotting difference against standard method is misleading.

      1 ,
      Lancet (London, England)
      Elsevier BV

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          Abstract

          When comparing a new method of measurement with a standard method, one of the things we want to know is whether the difference between the measurements by the two methods is related to the magnitude of the measurement. A plot of the difference against the standard measurement is sometimes suggested, but this will always appear to show a relation between difference and magnitude when there is none. A plot of the difference against the average of the standard and new measurements is unlikely to mislead in this way. We show this theoretically and by a practical example.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          0140-6736
          0140-6736
          Oct 21 1995
          : 346
          : 8982
          Affiliations
          [1 ] Department of Public Health Sciences, St George's Hospital Medical School, London, UK.
          Article
          S0140-6736(95)91748-9
          10.1016/s0140-6736(95)91748-9
          7564793
          ad32fd70-cdfe-48f2-8321-5f53b67d55f5

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