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      Letter to the editor: Covid-19 And Vit-D: Disease Mortality Negatively Correlates With Sunlight Exposure

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          Abstract

          The manuscript “Covid-19 And Vit-D: Disease Mortality Negatively Correlates with Sunlight Exposure” held our attention as we found fatal shortcomings that invalidates the analyses and conclusions.

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          Covid-19 And Vit-D: Disease Mortality Negatively Correlates With Sunlight Exposure

          The novel COVID-19 disease is a contagious acute respiratory infectious disease whose causative agent has been demonstrated to be a new virus of the coronavirus family, SARS-CoV-2. Alike with other coronaviruses, some studies show a COVID-19 neurotropism, inducing de-myelination lesions as encountered in Guillain-Barré syndrome. In particular, an Italian report concluded that there is a significant vitamin D deficiency in COVID-19 infected patients. In the current study, we applied a Pearson correlation test to public health as well as weather data, in order to assess the linear relationship between COVID-19 mortality rate and the sunlight exposure. For instance in continental metropolitan France, average annual sunlight hours are significantly (for a p-value of 1.532 × 10−32) correlated to the COVID-19 mortality rate, with a Pearson coefficient of -0.636. This correlation hints at a protective effect of sunlight exposure against COVID-19 mortality. This paper is proposed to foster academic discussion and its hypotheses and conclusions need to be confirmed by further research.
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            Author and article information

            Contributors
            Journal
            Spat Spatiotemporal Epidemiol
            Spat Spatiotemporal Epidemiol
            Spatial and Spatio-Temporal Epidemiology
            Elsevier Ltd.
            1877-5845
            1877-5853
            24 August 2020
            24 August 2020
            : 100373
            Affiliations
            [a ]Univ Rennes, CHU Rennes, Inserm, CIC 1414 (Centre d'Investigation Clinique de Rennes), F- 35000 Rennes, France
            [b ]Previously senior consultant. Alcohol Treatment Unit, University Hospital, Amiens, France
            [c ]Department of Biostatistics, CHU Rouen, Rouen, Normandie, France
            Author notes
            [* ]Corresponding author. University of Rennes 1, Clinical Investigation Center (INSERM 1414) and Adult Psychiatry Department, Rennes University Hospital, Rennes, France. Florian.NAUDET@ 123456chu-rennes.fr
            Article
            S1877-5845(20)30051-4 100373
            10.1016/j.sste.2020.100373
            7444493
            ad93862a-8f6c-4666-9412-3ceb5aec294c
            © 2020 Elsevier Ltd. All rights reserved.

            Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

            History
            : 13 August 2020
            : 17 August 2020
            Categories
            Article

            covid-19,vitamine d,bias,scientific integrity,reproducibility

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