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Novel vitamin D analogs as potential therapeutics: metabolism, toxicity profiling, and antiproliferative activity.
Author(s):
Jianjun Chen
1
,
Jin Wang
,
Tae-Kang Kim
,
Elaine W Tieu
,
Edith K Y Tang
,
Zongtao Lin
,
Dianne Kovacic
,
Duane D Miller
,
Arnold Postlethwaite
,
Robert C Tuckey
,
Andrzej T Slominski
,
Wei Li
Publication date
(Electronic):
May 2014
Journal:
Anticancer research
Keywords:
20(OH)D3 analogs
,
VDR translocation
,
hypercalcemic effect
,
liver microsomal stability
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There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
To discover novel [20(OH)D3] analogs as antiproliferative therapeutics.
Related collections
Cancer Metabolism
Author and article information
Journal
Journal ID (iso-abbrev):
Anticancer Res.
Title:
Anticancer research
ISSN (Electronic):
1791-7530
ISSN (Print):
0250-7005
Publication date (Electronic):
May 2014
Volume
: 34
Issue
: 5
Affiliations
[
1
]
Department of Pharmaceutical Science, University of Tennessee Health Science Center, 847 Monroe Avenue, Memphis, TN 38163, U.S.A. wli@uthsc.edu.
Article
Publisher Item ID:
34/5/2153
Mid ID:
NIHMS576636
PMC ID:
4015637
PubMed ID:
24778017
SO-VID:
adbf8b6a-aa4e-4806-80d9-c4273669626c
History
Keywords:
20(OH)D3 analogs
,
VDR translocation
,
hypercalcemic effect
,
liver microsomal stability
Data availability:
Keywords:
20(OH)D3 analogs
,
VDR translocation
,
hypercalcemic effect
,
liver microsomal stability
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…
Protective effects of novel derivatives of vitamin D 3 and lumisterol against UVB-induced damage in human keratinocytes involve activation of Nrf2 and p53 defense mechanisms
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…
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,
Tae-Kang Kim
,
Zorica Janjetovic
…
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