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Abstract
Thirty Klinefelter males treated with testosterone were studied by a follow-up examination
carried out an average of 3.6 years after treatment began. The age of the men averaged
25.5 years at the time of the follow-up. Seventy-seven per cent of the men were judged
to have benefited from testosterone treatment. They showed better mood, less irritability,
more energy and drive, less tiredness, more endurance and strength, less need for
sleep, better concentration ability and better relations with others during testosterone
treatment. The beneficial effects of testosterone persisted in some of the men after
cessation of treatment. The findings show that Klinefelter males given testosterone
for the first time as adults can benefit from such treatment, even though it is preferable
to start treatment at the age of 11-12 years.