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      Prevalence of human herpesvirus-8 among HIV-infected patients, intravenous drug users and the general population in Iran.

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          Abstract

          Studies looking at the frequency of human herpesvirus-8 (HHV-8) among Iranian blood donors have produced conflicting results. The aim of this study was to investigate the prevalence of HHV-8 DNA by using polymerase chain reaction methods among 168 healthy individuals, 60 intravenous drug users and 100 HIV-infected patients from Iran. The prevalence of HHV-8 was significantly higher among intravenous drug users (13.3%) compared with the general population (3.6%; P=0.017). The HHV-8 genome was mostly detected among intravenous drug users who displayed high-risk sexual behaviours. Moreover, the HHV-8 genome was also detected in 8% of HIV-infected patients. The present study findings support the likelihood that the transmission of HHV-8 is via a sexual route in the Iranian population.

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          Author and article information

          Journal
          Sex Health
          Sexual health
          CSIRO Publishing
          1448-5028
          1448-5028
          June 2016
          : 13
          : 3
          Affiliations
          [1 ] Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran 14155, Iran.
          [2 ] Department of Virology, Pasteur Institute of Iran, Tehran 1316943551, Iran.
          [3 ] Department of Immunology, Faculty of Medicine, Iran University of Medical Sciences, Tehran 157856171, Iran.
          [4 ] Department of Immunology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, Iran.
          Article
          SH15192
          10.1071/SH15192
          26886227

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