Beta-amyloid deposition and cognitive function in patients with major depressive disorder with different subtypes of mild cognitive impairment: (18)F-florbetapir (AV-45/Amyvid) PET study.

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Abstract

The objective of this study was to evaluate the amyloid burden, as assessed by (18)F-florbetapir (AV-45/Amyvid) positron emission tomography PET, in patients with major depressive disorder (MDD) with different subtypes of mild cognitive impairment (MCI) and the relationship between amyloid burden and cognition in MDD patients.

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Journal

Journal ID (iso-abbrev): Eur. J. Nucl. Med. Mol. Imaging

Title: European journal of nuclear medicine and molecular imaging

ISSN (Electronic): 1619-7089

ISSN (Print): 1619-7070

Publication date (Electronic): Jun 2016

Volume: 43

Issue: 6

Affiliations

[1 ] Department of Psychiatry, Chang Gung Memorial Hospital and Chang Gung University, Tao-Yuan, Taiwan.

[2 ] Department of Psychiatry, Kaohsiung Medical University Hospital and College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

[3 ] Department of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital, 5. Fu-Hsing Street, Kuei Shan Hsiang, Taoyuan, Taiwan.

[4 ] Department of Medical Imaging and Radiological Sciences and Healthy Aging Research Center, Chang Gung University, Tao-Yuan, Taiwan.

[5 ] Department of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital, 5. Fu-Hsing Street, Kuei Shan Hsiang, Taoyuan, Taiwan. lin4857@adm.cgmh.org.tw.

[6 ] Department of Medical Imaging and Radiological Sciences and Healthy Aging Research Center, Chang Gung University, Tao-Yuan, Taiwan. lin4857@adm.cgmh.org.tw.

Article

Publisher Item ID: 10.1007/s00259-015-3291-3

DOI: 10.1007/s00259-015-3291-3

PubMed ID: 26739329

SO-VID: ae09f728-3802-4660-ad2c-9fb4a4e7fb18

History

Keywords: 18F-Florbetapir (AV-45/Amyvid),Alzheimer’s disease,Amyloid,Dementia,Major depressive disorder,Mild cognitive impairment

Data availability:

Keywords: 18F-Florbetapir (AV-45/Amyvid), Alzheimer’s disease, Amyloid, Dementia, Major depressive disorder, Mild cognitive impairment

Beta-amyloid deposition and cognitive function in patients with major depressive disorder with different subtypes of mild cognitive impairment: (18)F-florbetapir (AV-45/Amyvid) PET study.

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Karger: Neurology and Neuroscience

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