Effects of endotoxin absorber hemoperfusion on microcirculation in septic pigs.

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Abstract

Endotoxins contribute to systemic inflammatory response and microcirculatory dysfunctions under conditions of sepsis. Polymyxin B hemoperfusion (PMX-HP) is used to remove circulating endotoxins and improve clinical outcomes. This study aims to investigate the effect of PMX-HP on microcirculation in septic pigs.

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Author and article information

Journal

Journal ID (iso-abbrev): J. Surg. Res.

Title: The Journal of surgical research

Publisher: Elsevier BV

ISSN (Electronic): 1095-8673

ISSN (Print): 0022-4804

Publication date (Electronic): May 01 2017

Volume: 211

Affiliations

[1 ] Department of Anesthesiology, National Taiwan University Hospital, Taipei, Taiwan.

[2 ] Graduate Institute of Physiology, National Taiwan University College of Medicine, Taipei, Taiwan.

[3 ] Division of Neurosurgery, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan; Institute of Medical Device and Imaging, National Taiwan University Hospital, Taipei, Taiwan.

[4 ] Department of Anesthesiology, Far Eastern Memorial Hospital, New Taipei, Taiwan. Electronic address: femhtylin@gmail.com.

Article

Publisher Item ID: S0022-4804(16)30576-5

DOI: 10.1016/j.jss.2016.12.026

PubMed ID: 28501124

SO-VID: ae1b1751-f14e-4c84-b50e-dff1ef962948

History

Keywords: Endotoxin,Hemoperfusion,Intestine,Microcirculation,Pig,Sepsis

Data availability:

Keywords: Endotoxin, Hemoperfusion, Intestine, Microcirculation, Pig, Sepsis

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