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      “Pain Relief is an Essential Human Right”, We Should be Concerned about It

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          Abstract

          Pain is a major public health issue throughout the world and represents a major clinical, social, and economic problem (1). The clinical, social, and economic costs of chronic pain in added health care costs, lost productivity, and lost income are significant, and if prolonged, it can cause distress, anxiety, and suffering. The burden that pain can place on individuals and the huge costs that society must bear as a result clearly indicate the need for collective thinking through a decision-making process (2). Acute pain is a major challenge worldwide, and chronic pain poses a massive disease burden, affecting an estimated 20% of adults, rising to 50% of the older population. In addition, cancer-related pain affects 70% of the 10 million cancer patients who are diagnosed annually, which is expected to double by 2020 (3). On October 11, 2004, the Global Day Against Pain, access to pain relief was promoted as an essential human right by the IASP, WHO, and European Federation of IASP Chapters (EFIC) (4, 5). Human rights refer to the concept of a universal right, regardless of legal jurisdiction or other localizing factors, such as ethnicity, nationality, and sex. The UN Universal Declaration of Human Rights conceptualizes human rights as based on inherent human dignity (3). Documents that were released at that time demonstrated that pain control has been a neglected area of governmental concern (6). There is a large and widening gap between the increasingly sophisticated knowledge of pain and its treatment and the effective application of that knowledge (7). Although the incidence of pain in developing countries is higher and cost-effective methods for pain care are available, acute and chronic pain is undertreated, and timely access to care is a growing problem in nations with access to the best health care (2, 8). Acute and chronic pain are often poorly managed for a wide variety of cultural, political, attitude-related, educational, and logistical reasons (8). Under treatment of pain is a poor medical practice that results in many adverse effects (7). Improvements in clinical pain care have not matched advances in scientific knowledge, and innovations in medical education on pain are needed. Several lines of evidence indicate that pain education needs to address the affective and cognitive dimensions of pain (9). The practice of pain medicine is affected by many market forces, including industry relationships with pain providers, lawmakers, and insurance companies; direct to consumer advertising; insurance reimbursement patterns; and competition among health care systems and pain management providers (10). These economic factors can encourage innovation and efficiency and may increase access to pain treatment. The Board of Directors of the American Board of Pain Medicine defined the specialty of pain medicine as follows: “the specialty of pain medicine is concerned with the prevention, evaluation, diagnosis, treatment and rehabilitation of painful disorders”. Interventional pain management is defined officially by National Uniform Claim Committee (NUCC) as “the discipline of medicine devoted to the diagnosis and treatment of pain and related disorders by the application of interventional techniques in managing subacute, chronic, persistent, and intractable pain, independently or in conjunction with other modalities of treatments”(11). Whereas anesthesiologists constitute the majority of physicians who treat chronic pain, other specialties, including psychiatry, physical medicine and rehabilitation, neurology, neurosurgery, and primary care (not mutually exclusive), are also heavily involved with chronic pain management. Development of pain medicine as a separate specialty does not prevent other specialties from managing pain syndromes or developing a multidisciplinary approach to pain management. The benefit of pain management by other disciplines is the appropriate and timely referral of these patients to pain specialists, which ultimately may be helpful to the patient (11). True pain practitioners stand ready, able, and willing to perform a comprehensive assessment, guide complex diagnostic evaluation, and offer a broad range of treatment options to patients with chronic and cancer-related pain. The growing tendency among Iranian anesthesiologists toward regional anesthesia and pain medicine in recent years spurred the establishment of the Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM) in November 2006 improve and support scientific and educational activities in this field, with the following goals: To standardize the indications, approaches, and techniques for regional anesthesia and pain interventions To maximize the exposure, education, and training of pain fellows To advance patient safety, cost effectiveness, and accountability To exchange and share new information, ideas, and innovations concerning regional anesthesia and pain management To encourage basic science as well as clinical outcome research in this field To promote information on regional anesthesia and pain procedures To preserve coverage for regional anesthesia and interventional pain management To encourage specialization and research in these areas To encourage the teaching of regional anesthesia and interventional pain procedures in all anesthesiology training programs Since 2006, ISRAPM stepped toward relieving pain by training pain medicine fellowships and conducting annual international ISRAPM seminars in interventional pain management. Considering the progressive interest in research projects on pain medicine, the lack of scientific journals that cover and share creative and innovative materials and articles was highlighted specially in Middle East and Asia. With the aim of disseminating updates on pain medicine and interventional pain, ISRAPM has published “Anesthesiology and Pain Medicine” since the summer of 2011. Anesthesiology and Pain Medicine is the official Journal of ISRAPM, covering clinical and basic research, education, patient care, health economics, and policy to inform all practitioners in pain management, such as anesthesiologists, interventional pain physicians, neurosurgeons, neurologists, and any specialists who are interested in pain medicine (12). The 4th national and 2nd International ISRAPM Congress will be held on October 28–30, 2011 in Tehran, Iran. Noting the requirement of wider sources of exchanging information, sharing data, and networking among researchers, ISRAPM aims to bolster networking between pain physicians and those who care about pain by holding workshops and speeches on interventional pain management and cutting-edge research locally, nationally, and internationally. On behalf of scientific and organizing committees, we are honored to invite you to join the ISRAPM Congress 2011: Interventional Pain Medicine, This meeting will address many of the issues facing us as medical practitioners who treat patients with various types of pain. Aspects of pain that will be addressed include neuropathic pain, back pain, cancer pain, palliative care, and acute pain management. Attention will be given to both the theory and practice of modern interventional pain treatment. The meeting will include lectures, workshops, and face to face “meet the expert” sessions. We hope to provide all our colleagues and friends with the opportunity to encounter new findings and technologies. We sincerely anticipate making the congress as a meeting point where all our colleagues and friends gather and exchange their latest knowledge and experiences in their fields.

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          A systematic review of the effect of waiting for treatment for chronic pain.

          In many countries timely access to care is a growing problem. As medical costs escalate health care resources must be prioritized. In this context there is an increasing need for benchmarks and best practices in wait-time management. The Canadian Pain Society struck a Task Force in December 2005 to identify benchmarks for acceptable wait-times for treatment of chronic pain. As part of the mandate a systematic review of the literature regarding the relationship between waiting times, health status and health outcomes for patients awaiting treatment for chronic pain was undertaken. Twenty-four studies met the inclusion criteria for the review. The current review supports that patients experience a significant deterioration in health related quality of life and psychological well being while waiting for treatment for chronic pain during the 6 months from the time of referral to treatment. It is unknown at what point this deterioration begins as results from the 14 trials involving wait-times of 10 weeks or less yielded mixed results with wait-times amounting to as little as 5 weeks, associated with deterioration. It was concluded that wait-times for chronic pain treatment of 6 months or longer are medically unacceptable. Further study is necessary to determine at what stage the deterioration begins from the onset of pain to treatment and the impact of waiting on treatment outcomes. Most important is the need to improve access to appropriate care for patients with chronic pain, an escalating public health care problem with significant human and economic costs.
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            Postoperative pain management

            The practice of modern anesthesiology has been developed from intraoperative period into perioperative period. Postoperative pain management is one of the most important components of adequate post-surgical patients care. This article wrote with the aim of emphasis on importance and effectiveness of post-operative pain management. Reading this article is beneficial for physicians, interventional pain managers and who care about pain medicine. Unrelieved acute pain after surgery usually elicits pathophysiologic neural alterations, including not only peripheral but also central sensitization which evolves into chronic pain syndromes. The main purpose of perioperative pain control is providing an adequate comfort level and acceptable side effects for patients. Effective postoperative analgesia improves patients’ outcome as observed by early ambulation, decrease in side effects, and reduce the incidence of postoperative chronic pain (1-3) Even though postoperative pain management and its implications have gained a significant attention in health care during last three decades, it continues to be a major challenge that still remains disregarded (4, 5). Postoperative analgesia has traditionally been provided by administration of opioid analgesics. However, excessive opioids administration is associated with a variety of side effects including ventilatory depression, drowsiness and sedation, nausea and vomiting, pruritus, ileus, urinary retention, and constipation. Prescription of multi-modal analgesic regimens contains non-opioid analgesics (e.g., local anesthetics, nonsteroidal anti-inflammatory drugs, cyclooxygenase inhibitors, acetaminophen, ketamine, clonidine, dexmedetomodine, gabapentin) as supplement of opioid analgesics can provide better postoperative pain management outcome. The opioid-sparing effects of these compounds may lead to reduced side effects of opioids (6). Nowadays variety of new drugs, analgesic techniques and devices, and preventive approaches are available for anesthesiologists, including patient-controlled analgesia (PCA), multimodal analgesia and pre-emptive analgesia. Besides, one of the most common methods for postoperative pain relief is PCA. This device is commonly assumed to imply on-demand intermittent, intravenous administration of opioids under patient control (with or without a continuous background infusion). PCA device is based on the use of a sophisticated microprocessor-controlled infusion pump that delivers a preprogrammed dosage of opioid analgesics when the patient pushes a demand button. Grass presented a more enlightened concept of PCA, noting that using any analgesic drugs under control of patient by any routes could be categorized as PCA, like patient-controlled epidural analgesia (PCEA) and patient-controlled regional analgesia (PCRA) (7). He proposed practical guidelines for the clinical usage of PCA, highlighted the complications and their management. To optimize the management of acute postoperative pain, basic mechanisms of postoperative pain must be explored and new treatments must continue to be developed. Tissue damages during surgery leads to two alterations in the responsiveness of the nociceptive system, peripheral sensitization and central sensitization. Pharmacological and non-pharmacological postoperative pain management should be started quickly to suppress the development of both peripheral and central sensitization, which involves both the primary afferent nociceptors and spinal dorsal horn neurons. Understanding the neuropharmacology of the spinal cord gives us the unbelievable opportunity to base clinical management on identified mechanisms of pain receptors, pathways, and mechanisms of action. Furthermore, evidence-based practice guidelines have the potential to provide valuable information to physicians and their patients. These guidelines not only provide guidance in routine practice, but they provide the “standard of care” for the specialists. Practice guidelines for anesthesiology and pain medicine must be improved by experts in these fields using the best available data obtained from a comprehensive review of the peer-reviewed medical literature.Anesthesiology and Pain Medicine, the official journal of Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM), aims at publishing of the scientific articles submitted by all the researchers and professionals in the field of anesthesiology and pain medicine from all over the world. It would be our pleasure to take our new steps toward medical excellence.
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              Economic burden of chronic pain.

              Pain represents a major clinical, social and economic problem, with estimates of its prevalence ranging from 8 to over 60%. The impact of pain on economies is enormous, with the cost of back pain alone equivalent to more than a fifth of one country's total health expenditure and 1.5% of its annual gross domestic product, while in another, it represents three-times the total cost of all types of cancer. However, decision makers have tended to concentrate their attention on a very minor component of the cost burden, namely prescription costs, which, in the case of back pain, represent 1% of the total cost burden. In addition to its economic impact, chronic pain is probably one of the diseases with the greatest negative impact on quality of life. For example, the quality of life for those with migraine has been shown to be at best equal to that for people with arthritis, asthma, diabetes mellitus or depression. The burden that pain imposes on individuals and the enormous costs that society has to bear as a result clearly demonstrate the need for collective thinking in the decision-making process. A broad, strategic perspective - based on evidence relating to effectiveness (including tolerability), efficiency and equity - is required in determining issues relating to the provision of services and resource allocation.
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                Author and article information

                Journal
                Anesth Pain Med
                Anesth Pain Med
                10.5812/aapm
                Kowsar
                Anesthesiology and Pain Medicine
                Kowsar
                2228-7523
                2228-7531
                26 September 2011
                Autumn 2011
                : 1
                : 2
                : 55-57
                Affiliations
                [1 ]Department of Anesthesiology and Pain Medicine, Tehran University of Medical Sciences, Tehran, Iran
                Author notes
                [* ]Corresponding author: Farnad Imani, Department of Anesthesiology and Pain Medicine, Rasoul-Akram Medical Center, Niyayesh St., Sattar Khaan Av., P O. Box: 1445613131, Tehran, Iran. Tel: +98-2166509059, Fax: +98-2166515758, E-mail: farimani@ 123456tums.ac.ir
                Article
                10.5812/kowsar.22287523.2306
                4335733
                ae1e0c42-56ec-4ccf-ad79-79f33f962fcc
                Copyright © 2011, ISRAPM, Published by Kowsar Corp.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 15 August 2011
                : 20 August 2011
                : 30 August 2011
                Categories
                Editorial

                anesthesia and analgesia,pain,illness burden,pain clinics,regional anesthesia

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