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      The promotion of salinomycin delivery to hepatocellular carcinoma cells through EGFR and CD133 aptamers conjugation by PLGA nanoparticles.

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          Abstract

          To develop salinomycin-loaded poly(lactic-co-glycolic acid) nanoparticles conjugated with both CD133 aptamers A15 and EGFR aptamers CL4 (CESN), to target hepatocellular carcinoma (HCC) cells simultaneously expressing EGFR and CD133.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Nanomedicine (Lond)
          Title: Nanomedicine (London, England)
          ISSN (Electronic): 1748-6963
          ISSN (Print): 1743-5889
          Publication date (Electronic): Jul 2015
          Volume: 10
          Issue: 12
          Affiliations
          [1 ] Department of Biliary-Hepatic Surgery, Affiliated Hospital of Guiyang Medical College, 28 Guiyi Road, Guizhou 550001, Guiyang, Guizhou, China.
          [2 ] International Join Cancer Institute, The Second Military Medical University, 800 Xiangyin Road, Shanghai 200433, China.
          [3 ] College of Pharmacy, The Second Military Medical University, 325 Guo He Road, Shanghai 200433, China.
          Article
          DOI: 10.2217/nnm.15.43
          PubMed ID: 26139123
          SO-VID: ae737f85-d90a-4aab-be5a-63e3fde8492b
          History

          Keywords: CD133,EGFR,hepatocellular carcinoma,nanoparticles,salinomycin
          Data availability:
          Keywords: CD133, EGFR, hepatocellular carcinoma, nanoparticles, salinomycin

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