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      Stem cell secretome-rich nanoclay hydrogel: a dual action therapy for cardiovascular regeneration.

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          Abstract

          A nanocomposite hydrogel with photocrosslinkable micro-porous networks and a nanoclay component was successfully prepared to control the release of growth factor-rich stem cell secretome. The proven pro-angiogenic and cardioprotective potential of this new bioactive system provides a valuable therapeutic platform for cardiac tissue repair and regeneration.

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          Author and article information

          Affiliations
          [1 ] BioIntel Research Laboratory, Department of Chemical and Petroleum Engineering, Bioengineering Graduate Program, School of Engineering, University of Kansas, Lawrence, KS, USA. arghyapaul@ku.edu.
          [2 ] SRM University, Kattankulathur 603203, Tamilnadu, India.
          [3 ] Department of Pathology, University of Cincinnati, 231-Albert Sabin Way, Cincinnati 45267, OH, USA.
          Journal
          Nanoscale
          Nanoscale
          Royal Society of Chemistry (RSC)
          2040-3372
          2040-3364
          Apr 14 2016
          : 8
          : 14
          26876936 10.1039/c5nr07806g 4863075 NIHMS781308

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