Stem cell secretome-rich nanoclay hydrogel: a dual action therapy for cardiovascular regeneration.

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Abstract

A nanocomposite hydrogel with photocrosslinkable micro-porous networks and a nanoclay component was successfully prepared to control the release of growth factor-rich stem cell secretome. The proven pro-angiogenic and cardioprotective potential of this new bioactive system provides a valuable therapeutic platform for cardiac tissue repair and regeneration.

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Journal

Journal ID (iso-abbrev): Nanoscale

Title: Nanoscale

Publisher: Royal Society of Chemistry (RSC)

ISSN (Electronic): 2040-3372

ISSN (Print): 2040-3364

Publication date (Electronic): Apr 14 2016

Volume: 8

Issue: 14

Affiliations

[1 ] BioIntel Research Laboratory, Department of Chemical and Petroleum Engineering, Bioengineering Graduate Program, School of Engineering, University of Kansas, Lawrence, KS, USA. arghyapaul@ku.edu.

[2 ] SRM University, Kattankulathur 603203, Tamilnadu, India.

[3 ] Department of Pathology, University of Cincinnati, 231-Albert Sabin Way, Cincinnati 45267, OH, USA.

Article

Mid ID: NIHMS781308

DOI: 10.1039/c5nr07806g

PMC ID: 4863075

PubMed ID: 26876936

SO-VID: ae8723d0-f349-499d-82ae-45c27b050144

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