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      Novel 10-kHz High-frequency Therapy (HF10 Therapy) Is Superior to Traditional Low-frequency Spinal Cord Stimulation for the Treatment of Chronic Back and Leg Pain: The SENZA-RCT Randomized Controlled Trial.

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          Abstract

          Current treatments for chronic pain have limited effectiveness and commonly known side effects. Given the prevalence and burden of intractable pain, additional therapeutic approaches are desired. Spinal cord stimulation (SCS) delivered at 10 kHz (as in HF10 therapy) may provide pain relief without the paresthesias typical of traditional low-frequency SCS. The objective of this randomized, parallel-arm, noninferiority study was to compare long-term safety and efficacy of SCS therapies in patients with back and leg pain.

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          Author and article information

          Journal
          Anesthesiology
          Anesthesiology
          1528-1175
          0003-3022
          Oct 2015
          : 123
          : 4
          Affiliations
          [1 ] From the Center for Clinical Research and Carolina's Pain Institute at Brookstown, Wake Forest Baptist Health, Winston-Salem, North Carolina (L.K.); Swedish Pain Center, Seattle, Washington (C.Y., T.Y.); The Pain Center of Arizona and HOPE Research Institute, Phoenix, Arizona (M.W.D.A.H.B.); Clinical and Regulatory Affairs, Nevro Corp., Menlo Park, California (B.E.G.); Millennium Pain Center, Bloomington, Illinois (R.V., R. Benyamin); Advanced Pain Therapy, PLLC, Hattiesburg, Mississippi (B.T.S.); IPM Medical Group, Inc., Walnut Creek, California (K.A.); Pain Consultants of Oregon, Eugene, Oregon (D.M.M.); Coastal Orthopedics and Pain Medicine, Bradenton, Florida (L.L.B., R. Bundschu); Comprehensive Pain and Rehabilitation, Pascagoula, Mississippi (T.L.Y.); and Houston Pain Associates, Houston, Texas (A.W.B.).
          Article
          10.1097/ALN.0000000000000774
          26218762

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