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Abstract
Cystic adventitial disease is a rare non-atheromatous cause of popliteal artery disease.
We report a case of a 54-year-old patient with claudication of the right calf caused
by cystic adventitial disease. Intra-operatively, a communication between the adventitia
and the knee joint was identified. Connections between the adventitial cyst and the
nearby joint have been reported in the literature that support the developmental theory.
This theory suggests that cystic adventitial disease is a developmental manifestation
of mucin-secreting cells derived from the mesenchyme of the adjacent joint. This case
is the first, to our knowledge, in which a communication between joint and adventitia
has been clearly documented by operative findings.